Recent Results in Cancer Research

New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors

Editors: Kreuser, Ernst D., Schlag, Peter M. (Eds.)

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About this book

This volume focuses on new and exciting approaches in the molecular and clinical management of gastrointestinal tumors. The first part presents recent insights into carcinogenesis, including alterations in cyclins and adhesion receptors, molecular structures which might be new targets of gene therapy. The second part of the volume offers new diagnostic tools, such as receptors for gastrointestinal hormones, proliferation markers, tumor suppressor proteins, and the multiple drug resistance gene, predicting response to therapy and prognosis in gastrointestinal tumors. The third part gives an update of successful approaches in primary and secondary prevention of colorectal carcinoma. Nutritional factors and pharmacologic agents can clearly decrease the risk, and fecal occult blood tests and endoscopy can reduce the mortality in colorectal carcinoma. Laparoscopic staging with subsequent biopsy of suspicious lymph nodes provides essential information in esophageal and gastric cancer. In locally advanced gastric cancer, preoperative chemotherapy provides sufficient evidence to investigate this approach as compared to primary surgery. Standards have recently been established in the adjuvant treatment of patients with gastrointestinal carcinoma, and promising new drugs, including monoclonal antibodies, thymidylate synthase, and topoisomerase inhibitors, as well as taxoids, are currently being tested in phase I, II, and III trials of gastrointestinal tumors.

Table of contents (24 chapters)

Table of contents (24 chapters)

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-3-642-80035-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase Institutional customers should get in touch with their account manager
Softcover $159.00
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors
Editors
  • Ernst D. Kreuser
  • Peter M. Schlag
Series Title
Recent Results in Cancer Research
Series Volume
142
Copyright
1996
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-80035-1
DOI
10.1007/978-3-642-80035-1
Softcover ISBN
978-3-642-80037-5
Series ISSN
0080-0015
Edition Number
1
Number of Pages
XII, 439
Number of Illustrations
9 illustrations in colour
Topics