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Current Topics in Microbiology and Immunology

HIV and Dementia

Proceedings of the NIMH-Sponsored Conference “Pathogenesis of HIV Infection of the Brain: Impact on Function and Behavior”

Editors: Oldstone, Michael, Vitkovic, Ljubisa (Eds.)

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  • ISBN 978-3-642-79657-9
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About this book

The National Institute of Mental Health (NIMH) AIDS Program is the fourth largest acquired immune deficiency syndrome (AIDS) program within the National Institutes of Health (NIH). Since 1983, our program's contributions have concentrated on two major areas. The first has been to develop effective strategies to prevent or reduce behaviors that place individuals at risk for human immunodeficiency virus type 1 (HIV-1) infection. The second has been to support and foster research to enhance our understanding of the profound impact of H IV-1 infection on the central nervous system (eNS). The brain appears to be a prime target of the virus and may serve as a reservoir for the virus. Post mortem examination of brain tissue has provided evidence of eNS cell damage in 80%-90% of people who die with AIDS. For about 10%-20% of people with AI DS, mild neuropsychological symptoms are the first signs of the disease. Approximately 20% of individuals infected with HIV-1 develop AIDS dementia complex. The symptoms include apathy, difficulty concentrat­ ing, irritability, depression, and personality changes. In the later stages of the disease, people may experience psychiatric disor­ ders. Death usually occurs within 6 months of the appearance of those more severe symptoms. Up to 90% of children infected with H IV-1 experience attention and concentration difficulties and often experience neurodevelopmental delay or regression over time.

Table of contents (17 chapters)

Table of contents (17 chapters)

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-3-642-79657-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA in USD
  • ISBN 978-3-642-79659-3
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
HIV and Dementia
Book Subtitle
Proceedings of the NIMH-Sponsored Conference “Pathogenesis of HIV Infection of the Brain: Impact on Function and Behavior”
Editors
  • Michael Oldstone
  • Ljubisa Vitkovic
Series Title
Current Topics in Microbiology and Immunology
Series Volume
202
Copyright
1995
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-79657-9
DOI
10.1007/978-3-642-79657-9
Softcover ISBN
978-3-642-79659-3
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XIII, 279
Topics