Handbook of Experimental Pharmacology

Toxicology of Metals

Biochemical Aspects

Editors: Goyer, Robert A., Cherian, M. George (Eds.)

Free Preview

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-3-642-79162-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Softcover $159.99
price for USA in USD
About this book

The toxicology of metals has been concerned in the past with effects that produced clinical signs and symptoms. However, this view of metal toxicology has expanded in recent years due principally to two advances. There has been a considerable increase in our knowledge of the biochemical effects of metals. In addition, biomarkers of toxicity can now be recognized that identify toxicity at levels of exposure that do not produce overt clinical effects. Thus, the toxicology of metals is now focused on nonclinical events that reflect adverse health effects. This new awareness has produced the challenge of determining the lowest adverse level of exposure. With increasing analytical sensitivity and methodologies to detect small changes at the molecular level, the lowest level of exposure of some toxic metals, like lead, is very small. Indeed, for metals in which there is no biologic requirement, it may be questioned whether there is a level of exposure that does not produce some degree of toxicity. For essential metals, the question is being asked as to the levels at which exposure exceeds biologic require­ ments and excess exposure becomes toxic. The appropriateness of health decisions and the formation of public policy are dependent on the availability of current scientific information that addresses these questions. The information in this volume is intended to be a resource for this purpose as well as a reference for students of toxicology and other health professionals.

Table of contents (19 chapters)

Table of contents (19 chapters)

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-3-642-79162-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Softcover $159.99
price for USA in USD
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Toxicology of Metals
Book Subtitle
Biochemical Aspects
Editors
  • Robert A. Goyer
  • M. George Cherian
Series Title
Handbook of Experimental Pharmacology
Series Volume
115
Copyright
1995
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-79162-8
DOI
10.1007/978-3-642-79162-8
Softcover ISBN
978-3-642-79164-2
Series ISSN
0171-2004
Edition Number
1
Number of Pages
XXII, 467
Topics