Nato ASI Subseries H:

Cellular Mechanisms of Sensory Processing

The Somatosensory System

Editors: Urban, Laszlo (Ed.)

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About this book

The research field of somatosensory processing in mammals has experienced revolutionary changes in recent years. Accumulation of basic and clinical data has greatly accelerated, and new phenomena have emerged. With the aid of new, refined methods, molecular and cellular changes have been described, underlying the signal transduction-transmission between the internal/external environment and the central nervous system have been described. The discovery of the interaction between the nervous and the immune system has, for example changed our view on the development of inflammatory diseases, while the cloning of genes encoding different trophic factors has boosted studies revealing profound changes in the regeneration of neurons, and induction of changes in phenotype. The study of the pre-and postsynaptic modulation of transmitter release, and the examination of the combined effects of amino acid and peptide transmitters has become recently possible by using cultured cell lines and in vitro techniques. Although it is in embryonic state, computational properties of single DRG cells under normal and pathological conditions are being investigated. Results soon or later will have a great impact on pain research and consequently ultimately in clinical pain management. This brief introduction indicates how our knowledge of the somatosensory system has increased dramatically recently. However, many investigators cultivate only a very specific field in the growing area of somatosensory research and find it difficult to integrate a more universal knowledge of their work.

Table of contents (27 chapters)

Table of contents (27 chapters)
  • Diversity of Somatic Spikes in Dorsal Root Ganglion Cells: Implications for Development, Function and Plasticity

    Mendell, Lorne M.

    Pages 3-18

  • Ion Channels Underlying Transduction and Adaptation in Mechanoreceptors

    French, Andrew S.

    Pages 19-34

  • Signal Transduction Processes in Sensorimotor Neurons of the Enteric Nervous System

    Surprenant, Annmarie

    Pages 35-45

  • Modulation of Voltage Dependent Calcium Channels by GABAb Receptors and G Proteins in Cultured Rat Dorsal Root Ganglion Neurons: Relevance to Transmitter Release and Its Modulation

    Dolphin, Annette C. (et al.)

    Pages 47-61

  • Signal Integration in the Axon Tree due to Branch Point Filtering Action

    Stoney, S. David, Jr.

    Pages 63-85

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-642-78762-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA in USD
  • ISBN 978-3-642-78764-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cellular Mechanisms of Sensory Processing
Book Subtitle
The Somatosensory System
Editors
  • Laszlo Urban
Series Title
Nato ASI Subseries H:
Series Volume
79
Copyright
1994
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-78762-1
DOI
10.1007/978-3-642-78762-1
Softcover ISBN
978-3-642-78764-5
Series ISSN
1010-8793
Edition Number
1
Number of Pages
XI, 502
Topics