Shop the Archives and get your next eBook for just 14.99! Stock up today >>

Growth Hormone and Somatomedins during Lifespan

Editors: Müller, Eugenio E., Cocchi, Daniela, Locatelli, Vittorio (Eds.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-642-78217-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $139.00
price for USA in USD
  • ISBN 978-3-642-78219-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The various congresses on growth hormone (GH) which have been held in Milan since 1967, the Milan Congresses, have witnessed over 25 years the tremendous expansion of a research field that was based initially upon the scarce knowledge of the biological properties of a protein. GH, whose chemical structure had just been identified and a radioimmunoassay developed for its measurement in blood, became in the following years a major area of biological research. The boundaries have since become blurred, as the research area has extended to the physiology and pathology of growth, puberty and reproduction, and the control of metabolism during the whole lifespan. Since the last GH Congress held in 1987, GH studies using the molecular biological approach have resulted in the puri­ fication, cloning and expression of the human GH (hGH) recep­ tor and binding protein, in new and exciting information on the insulin-like growth factors (IGF) and their paracrine and autocrine roles, and in the awareness that a panoply of binding proteins are present in the extracellular fluids and can, possibly, modulate IGF-receptor interactions and, thus, IGF actions. Finally, the availability of large amounts of biosynthetic hGH, besides allow­ ing more extensive clinical use in states of GH deficiency and extrasomatotrophic pathologies, has permitted disclosure of im­ portant metabolic effects of hGH during adulthood and, perhaps, aging and in many protein catabolic states.

Table of contents (28 chapters)

  • Growth Hormone: Neural Mechanisms of Control at Neonatal and Aged Periods

    Locatelli, V. (et al.)

    Pages 3-18

  • Studies on Peptide 23: A GHRH-Regulated Protein of the Pituitary and Gastrointestinal Tract

    Katsumata, N. (et al.)

    Pages 19-25

  • Biochemistry and Cellular Distribution of the Growth Hormone Receptor

    Waters, M. J. (et al.)

    Pages 26-43

  • Cellular Transfection of GH Receptor cDNA to Study GH Action

    Norstedt, G. (et al.)

    Pages 44-51

  • Molecular Biology of the Somatomedins

    Adamo, M. L. (et al.)

    Pages 55-64

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-642-78217-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $139.00
price for USA in USD
  • ISBN 978-3-642-78219-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Growth Hormone and Somatomedins during Lifespan
Editors
  • Eugenio E. Müller
  • Daniela Cocchi
  • Vittorio Locatelli
Copyright
1993
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-78217-6
DOI
10.1007/978-3-642-78217-6
Softcover ISBN
978-3-642-78219-0
Edition Number
1
Number of Pages
XV, 343
Number of Illustrations and Tables
22 b/w illustrations
Topics