The World of Peptides
A Brief History of Peptide Chemistry
Authors: Wieland, Theodor, Bodanszky, Miklos
Free PreviewBuy this book
- About this book
-
Almost two centuries ago proteins were recognized as the primary materials (proteios = primary) oflife, but the significance and wide role of peptides (from pepsis = digestion) in practically all life pro cesses has only become apparent in the last few decades. Biologi cally active peptides are now being discovered at rapid intervals in the brain and in other organs including the heart, in the skin of amphibians and many other tissues. Peptides and peptide-like compounds are found among toxins and antibiotics. It is unlikely that this process, an almost explosive broadening of the field, will come to a sudden halt. By now it is obvious that Nature has used the combination of a small to moderate number of amino acids to generate a great variety of agonists with specific and often highly sophisticated functions. Thus, peptide chemistry must be regarded as a discipline in its own right, a major branch of biochemistry, fairly separate from the chemistry of proteins. Because of the important role played by synthesis both in the study and in the practical preparation of peptides, their area can be considered as belonging to bio-organic chemistry as well. The already overwhelming and still increasing body of know ledge renders an account of the history of peptide chemistry more and more difficult. It appears therefore timely to look back, to take stock and to recall the important stages in the development of a new discipline.
- Table of contents (10 chapters)
-
-
Introduction. Amino Acids and a Few Early Paradigmatic Peptides
Pages 1-22
-
Syntheses of Peptides. The First Epoch
Pages 23-43
-
The Era After Emil Fischer. The Carbobenzoxy Group, Max Bergmann and His Scientific Circle
Pages 44-76
-
A Second Breakthrough: New Methods for the Formation of the Peptide Bond
Pages 77-102
-
A New Technology: Solid Phase Peptide Synthesis
Pages 103-112
-
Table of contents (10 chapters)
Recommended for you
Bibliographic Information
- Bibliographic Information
-
- Book Title
- The World of Peptides
- Book Subtitle
- A Brief History of Peptide Chemistry
- Authors
-
- Theodor Wieland
- Miklos Bodanszky
- Copyright
- 1991
- Publisher
- Springer-Verlag Berlin Heidelberg
- Copyright Holder
- Spinger-Verlag Berlin Heidelberg
- eBook ISBN
- 978-3-642-75850-8
- DOI
- 10.1007/978-3-642-75850-8
- Softcover ISBN
- 978-3-642-75852-2
- Edition Number
- 1
- Number of Pages
- XIII, 298
- Topics
