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Current Topics in Pathology

Reaction Patterns of the Lymph Node

Part 2 Reactions Associated with Neoplasia and Immune Deficient States

Editors: Grundmann, E., Vollmer, E. (Eds.)

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About this book

This second volume reports on the reaction patterns of lymph nodes in neoplastic and immunodeficient diseases. Based on the contents of volume 1, it presents a detailed survey of lymph node structures and their cellular components under these conditions. The patterns of nodal reactions to the development and spread of cancer have recently been investigated and discussed by several authors. Here, the immediate interactions between tumor tissue and the regional nodes have been assessed in experimental models and in human material. Using modern morphological methods such as im­ munohistochemistry on the light and electron microscopic level, new insights have been gained into the stepwise process of lymphogenous metastasis. Macrophages/reticulum cells were found to playa signifi­ cant role in this process, which is duly emphasized. Based on appro­ priate animal models, one chapter focuses on various subtypes of these cellular elements and their role in the two separate phases of tumor spread and the development of true metastases. The induction of fibronectin in lymph nodes is effected by tumor cells forming a special part of the extracellular matrix. The multifunctional fibronec­ tin molecule serves as a mediator between tumor cells and fibroblasts, furthering the formation of tumor stroma. This volume also contains a comprehensive survey of primary im­ munodeficiency syndromes and their nodal manifestations, reference being made to the most recent immunological knowledge.

Table of contents (6 chapters)

Table of contents (6 chapters)
  • Reaction Patterns of Lymph Nodes in the Development and Spread of Cancer

    Pages 1-34

    Vollmer, E. (et al.)

  • Patterns of Fibronectin Induction in Lymph Nodes Affected by Metastatic Growth of Adenocarcinomas

    Pages 35-47

    Beck, N. (et al.)

  • Macrophages/Reticulum Cells in Early and Late Phases of Lymphogenous Metastasis

    Pages 49-79

    Vollmer, E. (et al.)

  • Primary Immunodeficiency Syndromes and Their Manifestations in Lymph Nodes

    Pages 81-155

    Cottier, H. (et al.)

  • Immunological Dysregulation of Lymph Nodes in AIDS Patients

    Pages 157-188

    Krueger, G. R. F. (et al.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-642-75522-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $139.99
price for USA in USD
  • ISBN 978-3-642-75524-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Reaction Patterns of the Lymph Node
Book Subtitle
Part 2 Reactions Associated with Neoplasia and Immune Deficient States
Editors
  • E. Grundmann
  • E. Vollmer
Series Title
Current Topics in Pathology
Series Volume
84/2
Copyright
1991
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-75522-4
DOI
10.1007/978-3-642-75522-4
Softcover ISBN
978-3-642-75524-8
Series ISSN
0070-2188
Edition Number
1
Number of Pages
IX, 225
Number of Illustrations
68 b/w illustrations
Topics