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Chemical Carcinogenesis and Mutagenesis II

  • Book
  • © 1990

Overview

Editors:
  1. Colin S. Cooper

    1. Chester Beatty Laboratories, The Institute of Cancer Research: Royal Cancer Hospital, London, Great Britain

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  2. Philip L. Grover

    1. Chester Beatty Laboratories, The Institute of Cancer Research: Royal Cancer Hospital, London, Great Britain

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 94 / 2)

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Table of contents (15 chapters)

  1. Front Matter

    Pages I-XXVI
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  2. Relationships Between Mutagenesis and Carcinogenesis

    1. Front Matter

      Pages 1-1
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    2. Use of Mutations in Bacteria as Indicators of Carcinogenic Potential

      • R. D. Callander
      Pages 3-26

    3. Mammalian Cell Mutations

      • C. F. Arlett
      Pages 27-50

    4. Mechanisms of Repair in Mammalian Cells

      • M. Defais
      Pages 51-70

    5. Cancer-Prone Human Disorders with Defects in DNA Repair

      • A. R. Lehmann, S. W. Dean
      Pages 71-101

    6. DNA Repair and Carcinogenesis by Alkylating Agents

      • A. E. Pegg
      Pages 103-131

  3. Modifiers of Chemical Carcinogenesis

    1. Front Matter

      Pages 133-133
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    2. Tumour Promotion: Biology and Molecular Mechanisms

      • A. W. Murray, A. M. Edwards, C. S. T. Hii
      Pages 135-157

    3. Inhibition of Chemical Carcinogenesis

      • J. DiGiovanni
      Pages 159-223

    4. Genetic Susceptibility to Chemical Carcinogens

      • D. G. Harnden
      Pages 225-248

    5. Interactive Effects Between Viruses and Chemical Carcinogens

      • A. Haugen, C. C. Harris
      Pages 249-268

  4. Oncogenes in Tumor Development

    1. Front Matter

      Pages 269-269
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    2. Human Oncogenes

      • A. Hall
      Pages 271-295

    3. Recessive Oncogenes and Anti-Oncogenes

      • J. K. Cowell
      Pages 297-318

    4. The Role of Oncogene Activation in Chemical Carcinogenesis

      • C. S. Cooper
      Pages 319-352

    5. Growth Factors and Their Receptors

      • C.-H. Heldin, B. Westermark
      Pages 353-379

    6. Signal Transduction in Proliferating Normal and Transformed Cells

      • M. J. O. Wakelam
      Pages 381-401

    7. Effect of Oncogenes on Cell Differentiation

      • D. Boettiger, D. Chalmers
      Pages 403-438

  5. Back Matter

    Pages 439-467
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Keywords

About this book

I have been privileged to witness and participate in the great growth of knowledge on chemical carcinogenesis and mutagenesis since 1939 when I entered graduate school in biochemistry at the University of Wisconsin­ Madison. I immediately started to work with the carcinogenic aminoazo dyes un­ der the direction of Professor CARL BAUMANN. In 1942 I joined a fellow graduate student, ELIZABETH CA VERT, in marriage and we soon commenced a joyous part­ nership in research on chemical carcinogenesis at the McArdle Laboratory for Cancer Research in the University of Wisconsin Medical School in Madison. This collaboration lasted 45 years. I am very grateful that this volume is dedi­ cated to the memory of Elizabeth. The important and varied topics that are reviewed here attest to the continued growth of the fields of chemical car­ cinogenesis and mutagenesis, including their recent and fruitful union with viral oncology. I feel very optimistic about the application of knowledge in these fields to the eventual solution of numerous problems, including the detection and estimation of the risks to humans of environmental chemical carcinogens and re­ lated factors.

Editors and Affiliations

  • Chester Beatty Laboratories, The Institute of Cancer Research: Royal Cancer Hospital, London, Great Britain

    Colin S. Cooper, Philip L. Grover

Bibliographic Information

  • Book Title: Chemical Carcinogenesis and Mutagenesis II

  • Editors: Colin S. Cooper, Philip L. Grover

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-642-74778-6

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1990

  • Softcover ISBN: 978-3-642-74780-9Published: 28 December 2011

  • eBook ISBN: 978-3-642-74778-6Published: 06 December 2012

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XXVI, 467

  • Topics: Pharmacology/Toxicology, Biochemistry, general, Oncology, Pharmacy

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