The Pathology of the Endocrine Pancreas in Diabetes

Editors: Lefebvre, Pierre J., Pipeleers, Daniel G. (Eds.)

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About this book

Diabetes mellitus represents one of the most frequent and serious clinical syn­ dromes in contemporary medicine. Since the end of the nineteenth century, the endocrine pancreas has been implicated in the pathogenesis of this disease. Several pathologists of the twentieth century detected various lesions and mor­ phologic alterations in the pancreatic islets of diabetic patients, but the patho­ physiologic basis of their findings remained long obscure. The systematic mi­ croscopic work of WILLY GEPTS clarified the views and related the variety in histopathology to differences in origin, duration and clinical expression of the disease. Over the past two decades, the concept of a multifactorial origin of diabetes has become widely accepted. Various agents and mechanisms have been identified which can lead to a quantitative or qualitative deficit in pancre­ atic B-cells. The purpose of this book is to bring an update on the many path­ ways which may induce an absolute or relative insufficiency in insulin release and hence a diabetic state. Rather than bringing a complete account on all re­ search relevant to the understanding of the pathology of the diabetic pancreas, the authors of the various chapters of this volume have focussed on selected processes which can impair B-cell function, survival or regeneration.

Table of contents (17 chapters)

Table of contents (17 chapters)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-642-72691-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $139.00
price for USA in USD
  • ISBN 978-3-642-72693-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Pathology of the Endocrine Pancreas in Diabetes
Editors
  • Pierre J. Lefebvre
  • Daniel G. Pipeleers
Copyright
1988
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
Distribution Rights
Distribution rights for Japan: Igaku Shoin, Tokyo
eBook ISBN
978-3-642-72691-0
DOI
10.1007/978-3-642-72691-0
Softcover ISBN
978-3-642-72693-4
Edition Number
1
Number of Pages
XI, 336
Topics