New Aspects in Hypertension Adrenoceptors

Symposium, November 1985, Munich

Editors: Middeke, M., Holzgreve, H. (Eds.)

Free Preview

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-642-71418-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $139.00
price for USA in USD
  • ISBN 978-3-642-71420-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book reports on the current state of knowledge about adreno­ ceptors and their involvement in the pathogenesis and treatment of high blood pressure. This is a relatively recent and extremely excit­ ing addition to the field of hypertension research. The development of new analytical procedures, such as radio ligand-binding methods, has made it possible to identify and quantify the adrenoceptors in different tissues and in circulating blood cells. As a consequence, much new and valuable information has been obtained. An under­ standing of the role of the fJ-adrenoceptor-adenylatecyclase-cAMP system in hypertension is one such product of this new approach. Both review articles and new experimental and clinical data are included in this volume. New aspects of the distribution, identifica­ tion and regulation, and the chronopharmacology of adrenoceptors, as well as beta blockade, will be highlighted. The clinical contributions concern the normal regulation of the fJ­ adrenoceptor-adenylatecyclase-cAMP system, and how it is altered in hypertensives as a possible mechanism in the pathogenesis and maintenance of essential hypertension. With this knowledge it is be­ coming easier to explain the molecular and cellular action behind the familiar role of the sympathico-adrenergic system in the devel­ opment of hypertension and the mechanism of beta blockade. The vast majority of the data available in this field is confined to periph­ eral mechanisms, owing to the limited possibilities for investigating the central nervous system under clinical conditions.

Table of contents (18 chapters)

Table of contents (18 chapters)
  • Central Nervous Noradrenergic and Adrenergic Systems and their Functions

    Pages 1-13

    Koella, W. P.

  • Peripheral Sympathoadrenal System: Transmitter Release and Distribution of Adrenoceptors

    Pages 14-24

    Göthert, M.

  • Characterization of Adrenoceptors: Receptor-Binding Studies and Agonist-Antagonist Interaction

    Pages 25-32

    Wellstein, A.

  • Agonist Interaction with α 2-Adrenoceptors of Human Platelets

    Pages 33-42

    Schloos, J. (et al.)

  • Regulation of the β-Adrenergic Receptor-Adenylate Cyclase System in Cardiac Membranes

    Pages 43-64

    Krawietz, W.

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-642-71418-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $139.00
price for USA in USD
  • ISBN 978-3-642-71420-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
New Aspects in Hypertension Adrenoceptors
Book Subtitle
Symposium, November 1985, Munich
Editors
  • M. Middeke
  • H. Holzgreve
Copyright
1986
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-71418-4
DOI
10.1007/978-3-642-71418-4
Softcover ISBN
978-3-642-71420-7
Edition Number
1
Number of Pages
XII, 233
Topics