Progress in Clinical Biochemistry and Medicine

Metabolic Control in Diabetes Mellitus Beta Adrenoceptor Blocking Drugs NMR Analysis of Cancer Cells Immunoassay in the Clinical Laboratory Cyclosporine

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About this book

The close association between blood glucose control and the well-being of the patient, as well as the risk for the development of the "late" complications of 3 diabetes, make it necessary to attain near normalisation of blood glucosel- ). Signifi­ cant progress has been made in this direction in the last few years because of the advancement of analytical techniques for the monitoring of both metabolic status and the functional state of the pancreas and the kidneys, organs involved in the disease process. The respective methodologies are the test strips for self-monitoring of glucose in blood and urine, the measurement of the nonenzymatic glycosylation of hemoglobin and serum proteins, the C-peptide assay, and the determination of small amounts of albumin in urine. The test strip methodology for determination of glucose in blood and urine has made possible home blood glucose monitoring which enables the patient to aim for treatment targets near the physiological range. To this information on short term glycemia obtained by the patient, the determination of hemoglobin glycosylation in the clinical chemistry laboratory adds quantitative information about averaged long­ term glycemic control. The C-peptide assay allows evaluation of the residual pancreatic function in the presence of exogenous insulin. Results of a C-peptide assay are helpful in selecting the appropriate treatment for poorly controlled maturity-onset diabetes. The detection of microalbuminuria, an abnormal albumin excretion below the level of "Albustix" detection, establishes nephropathy before renal damage becomes irreversible.

Table of contents (5 chapters)

Table of contents (5 chapters)
  • Monitoring of Metabolic Control in Diabetes Mellitus: Methodological and Clinical Aspects

    Pages 1-27

    Flückiger, Rudolf (et al.)

  • Recent Chemical Developments in the Field of Beta Adrenoceptor Blocking Drugs

    Pages 29-72

    Köppe, Herbert G.

  • NMR Analysis of Cancer Cells

    Pages 73-112

    Mountford, Carolyn E. (et al.)

  • The Role of Immunoassay in the Clinical Laboratory

    Pages 113-155

    Nickoloff, Eileen L., Ph.D.

  • Cyclosporine: Chemistry, Structure-Activity Relationships and Mode of Action

    Pages 157-191

    Wenger, Roland M. (et al.)

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-3-642-70998-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA in USD
  • ISBN 978-3-642-71000-1
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Metabolic Control in Diabetes Mellitus Beta Adrenoceptor Blocking Drugs NMR Analysis of Cancer Cells Immunoassay in the Clinical Laboratory Cyclosporine
Series Title
Progress in Clinical Biochemistry and Medicine
Series Volume
3
Copyright
1986
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-70998-2
DOI
10.1007/978-3-642-70998-2
Softcover ISBN
978-3-642-71000-1
Series ISSN
0177-8757
Edition Number
1
Number of Pages
VIII, 192
Topics