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Bayer-Symposium

The Pathogenesis of Bacterial Infections

Editors: Jackson, George G., Thomas, Herbert (Eds.)

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About this book

G. G. Jackson The pathogenesis of bacterial infection defines the dynamics at an interface of ecologic association of bacteria and host. First, it occurs at the portal of initial contact with a per­ missive target cell. The infected cell provides either a passive or a specific receptor for the bacterium or its products, to­ gether with ligands and an environment of helper and inhibiting factors. The result is bacterial replication to produce an im­ balance of a potentially commensal relation which, under other defined conditions, would be optimal for the survival of both the host and bacterial cells. Virulence and pathogenesis are both absolute and relative terms. They must be interpreted strictly according to the circumstances of site-specific inter­ actions of bacterial and host cells, membrane composition, structure, characteristics, and environmental substances. The bacteria themselves may have, acquire, or switch on or off under certain conditions, the products or properties that produce cellular damage that we recognize as virulence. Another result of bacterial infection may be to stimulate a normal host cell function to perform at a pathophysiologic level, causing illness that we recognize as virulence. A third marker of virulence may be the ability to invade a cell or tissue barrier and produce a pathologic effect at a site that is remote from the portal of commensal association or pathologic entry.

Table of contents (48 chapters)

Table of contents (48 chapters)

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-3-642-70351-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
The Pathogenesis of Bacterial Infections
Editors
  • George G. Jackson
  • Herbert Thomas
Series Title
Bayer-Symposium
Series Volume
8
Copyright
1985
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-70351-5
DOI
10.1007/978-3-642-70351-5
Softcover ISBN
978-3-642-70353-9
Series ISSN
0067-4672
Edition Number
1
Number of Pages
XVI, 432
Topics

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