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Current Topics in Microbiology and Immunology

Current Topics in Microbiology and Immunology

Authors: Cooper, M., Hofschneider, P.H., Koprowski, H., Melchers, F., Rott, R., Schweiger, H.G., Vogt, P.K., Zinkernagel, R.

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About this book

Binding of various ligands (hormones, neurotransmitters, immunological stimuli) to membrane receptors induces the following changes: 1. Receptor redistribution (clustering, "capping") 2. Conformational changes that can be detected by fluorescent probes 3. Alteration in membrane fluidity (spin label and fluorescence polarization probes) 4. Changes in fluxes of ions and metabolites 5. Increased phospholipid turnover (especially of phosphatidyl inositol) 6. Activation of membrane-bound enzymes (adenyl cyclase, ATPase, transmethylases). Some of the early changes resulting from or associated with the binding (adsorption) of virions to the host cell membrane are of the same type. Adsorption of animal viruses to cells is the ftrst step in a chain of events resulting in the production of progeny virus on the one hand and in damage to cells and tissues on the other. In the classical studies of viral infection, cells are adsorbed with virus, usually for 60 min, and the changes induced by the virus in the host cell are recorded thereafter. In the past decade, more and more studies have been aimed at the events occurring in these ftrst 60 min of the so-called adsorption period. These studies deal with the nature of adsorption, e. g. , the ligand-receptor type of interaction between the virus and the cell membrane. Many receptors for viruses were identifted and so were the viral proteins which take part in adsorption.

Table of contents (4 chapters)

  • Biosynthesis of the Collagen-like C1q Molecule and its Receptor Functions for Fc and Polyanionic Molecules on Macrophages

    Loos, Michael

    Pages 1-56

  • Changes Induced in Cell Membranes Adsorbing Animal Viruses, Bacteriophages, and Colicins

    Fuchs, Pinhas (et al.)

    Pages 57-99

  • Fatty Acid Binding: A New Kind of Posttranslational Modification of Membrane Proteins

    Schmidt, Michael F. G.

    Pages 101-129

  • Escherichia coli Virus T1: Genetic Controls During Virus Infection

    Wagner, Erwin F. (et al.)

    Pages 131-152

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-642-68906-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA in USD
  • ISBN 978-3-642-68908-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Current Topics in Microbiology and Immunology
Authors
Series Title
Current Topics in Microbiology and Immunology
Series Volume
102
Copyright
1983
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-68906-2
DOI
10.1007/978-3-642-68906-2
Softcover ISBN
978-3-642-68908-6
Series ISSN
0070-217X
Edition Number
1
Number of Pages
IV, 154
Topics