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Current Topics in Microbiology and Immunology

Volume 102

  • Book
  • © 1983

Overview

Editors:
  1. M. Cooper

    1. Birmingham, USA

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  2. P. H. Hofschneider

    1. Martinsried, Germany

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  3. H. Koprowski

    1. Philadelphia, USA

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  4. F. Melchers

    1. Basel, Switzerland

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  5. R. Rott

    1. Gießen, Germany

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  6. H. G. Schweiger

    1. Ladenburg, Heidelberg, Germany

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  7. P. K. Vogt

    1. Los Angeles, USA

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  8. R. Zinkernagel

    1. Zürich, Switzerland

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Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 102)

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Table of contents (4 chapters)

  1. Front Matter

    Pages i-iii
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  2. Biosynthesis of the Collagen-like C1q Molecule and its Receptor Functions for Fc and Polyanionic Molecules on Macrophages

    • Michael Loos
    Pages 1-56

  3. Changes Induced in Cell Membranes Adsorbing Animal Viruses, Bacteriophages, and Colicins

    • Pinhas Fuchs, Alexander Kohn
    Pages 57-99

  4. Fatty Acid Binding: A New Kind of Posttranslational Modification of Membrane Proteins

    • Michael F. G. Schmidt
    Pages 101-129

  5. Escherichia coli Virus T1: Genetic Controls During Virus Infection

    • Erwin F. Wagner, Bernhard Auer, Manfred Schweiger
    Pages 131-152

  6. Back Matter

    Pages 153-154
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Keywords

About this book

Binding of various ligands (hormones, neurotransmitters, immunological stimuli) to membrane receptors induces the following changes: 1. Receptor redistribution (clustering, "capping") 2. Conformational changes that can be detected by fluorescent probes 3. Alteration in membrane fluidity (spin label and fluorescence polarization probes) 4. Changes in fluxes of ions and metabolites 5. Increased phospholipid turnover (especially of phosphatidyl inositol) 6. Activation of membrane-bound enzymes (adenyl cyclase, ATPase, transmethylases). Some of the early changes resulting from or associated with the binding (adsorption) of virions to the host cell membrane are of the same type. Adsorption of animal viruses to cells is the ftrst step in a chain of events resulting in the production of progeny virus on the one hand and in damage to cells and tissues on the other. In the classical studies of viral infection, cells are adsorbed with virus, usually for 60 min, and the changes induced by the virus in the host cell are recorded thereafter. In the past decade, more and more studies have been aimed at the events occurring in these ftrst 60 min of the so-called adsorption period. These studies deal with the nature of adsorption, e. g. , the ligand-receptor type of interaction between the virus and the cell membrane. Many receptors for viruses were identifted and so were the viral proteins which take part in adsorption.

Editors and Affiliations

  • Birmingham, USA

    M. Cooper

  • Martinsried, Germany

    P. H. Hofschneider

  • Philadelphia, USA

    H. Koprowski

  • Basel, Switzerland

    F. Melchers

  • Gießen, Germany

    R. Rott

  • Ladenburg, Heidelberg, Germany

    H. G. Schweiger

  • Los Angeles, USA

    P. K. Vogt

  • Zürich, Switzerland

    R. Zinkernagel

Bibliographic Information

  • Book Title: Current Topics in Microbiology and Immunology

  • Book Subtitle: Volume 102

  • Editors: M. Cooper, P. H. Hofschneider, H. Koprowski, F. Melchers, R. Rott, H. G. Schweiger, P. K. Vogt, … R. Zinkernagel

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-68906-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 1983

  • Softcover ISBN: 978-3-642-68908-6Published: 07 December 2011

  • eBook ISBN: 978-3-642-68906-2Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: IV, 154

  • Topics: Medical Microbiology, Virology

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