Current Topics in Pathology

Carcinogenesis

Editors: Grundmann, E. (Ed.)

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1. Concepts on the Causal Genesis of Human Intestinal Tumors The action of chemical substances has a significant role in the genesis of human tumors. It is assumed that most human tumors are induced by exogenous chemical noxae (Schmahl, 1970;Heidelberger, 1975; and others). In the course of intensive efforts to discover the principles of tumor etiology, important insights have resulted in recent years. These are that chemical carcinogens do not only arise as products of our tech­ nological civilization, but that they also occur in nature as potent solitary carcinogens and cocarcinogens (e. g. , as plant products). For review, see Hecker (1972) and Preuss­ mann (1975). Not only "complete" carcinogens are significant for the genesis of tu­ mors, but also substances which are first transformed to the actual carcinogenic com­ pound in the organism (Schmahl, 1975). The causal significance of exogenous noxae in carcinogenesis is indicated by the fact emphasized by Bauer (1963) that malignant tumors occur predilectively at those sites in the body which are in direct or indirect contact with the environment. This applies especially to the intestinal tract.

Table of contents (4 chapters)

Table of contents (4 chapters)

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-642-67292-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA in USD
  • ISBN 978-3-642-67294-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Carcinogenesis
Editors
  • E. Grundmann
Series Title
Current Topics in Pathology
Series Volume
67
Copyright
1979
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-67292-7
DOI
10.1007/978-3-642-67292-7
Softcover ISBN
978-3-642-67294-1
Series ISSN
0070-2188
Edition Number
1
Number of Pages
VI, 259
Topics