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Current Topics in Microbiology and Immunology

Current Topics in Microbiology and Immunology / Ergebnisse der Microbiologie und Immunitätsforschung

Authors: Arber, W., Haas, R., Henle, W., Hofschneider, P.H., Humphrey, J.H., Jerne, N.K., Koldovský, P., Koprowski, H., Maaløe, O., Rott, R., Schweiger, H.G., Sela, M., Syru?ek, L., Vogt, P.K., Wecker, E.

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About this book

Prominent progress in molecular biology was only made when it became possible to separate functionally distinct molecules by taking advantage of their biophysical properties. Likewise, the analysis of the functions of hetero­ geneous populations of immunocompetent cells, as to the functional properties of their various subpopulations, can not be done until these can be isolated in reasonably pure form by selective fractionation. During the last few years significant advances have been made in this field, and cells have been separated according to size, density or charge (MILLER et aI. , 1969; SHORTMAN, 1968; ANDERSSON, 1973 c), or by taking advantage of more specific surface markers to allow selective depletion or enrichment of a given subpopulation of cells (WIGZELL and ANDERSSON, 1971). Although separation techniques have been used in a variety of cellular systems, they have been particularly useful in the study of reticuloendothelial cells and primarily in the study of cells partici­ pating in the immune responses. Quite extensive reviews have been written which well cover the methods used for separation of cells and the results obtained with the various approaches (WIGZELL and ANDERSSON, 1971; SHORTMAN, 1972). To review this work is becoming a more and more voluminous task. As data rapidly accumulate, we will not try to make such a complete review.

Table of contents (4 chapters)

Table of contents (4 chapters)
  • Specific Fractionation of Immunocompetent Cells

    Pages 1-42

    Wigzell, H. (et al.)

  • Decoding of Regulatory Signals at the Microbial Surface

    Pages 43-96

    Reissig, José L.

  • Predicting what Antibodies an Antigen will Induce: The Inadequacy of the Determinant Model

    Pages 97-111

    Cunningham, A. J.

  • Cell-Mediated Immunity in Certain Parasitic Infections

    Pages 113-137

    Larsh, John E., Jr. (et al.)

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  • ISBN 978-3-642-65912-6
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Bibliographic Information

Bibliographic Information
Book Title
Current Topics in Microbiology and Immunology / Ergebnisse der Microbiologie und Immunitätsforschung
Authors
Series Title
Current Topics in Microbiology and Immunology
Series Volume
67
Copyright
1974
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag, Berlin · Heidelberg
eBook ISBN
978-3-642-65912-6
DOI
10.1007/978-3-642-65912-6
Softcover ISBN
978-3-642-65914-0
Series ISSN
0070-217X
Edition Number
1
Number of Pages
IV, 162
Topics