Read While You Wait - Get immediate ebook access, if available*, when you order a print book

Recent Results in Cancer Research

Risk and Progression Factors in Carcinogenesis

Editors: Müller-Hermelink, H.K., Neumann, H.G., Dekant, W. (Eds.)

Free Preview

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-3-642-60393-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA in USD
  • ISBN 978-3-642-64385-9
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
About this book

The principal goal of experimental carcinogenesis is the elucidation of mechanisms and factors that might be of relevance for the formation of human tumors. Specialization, as necessary as it may be, however, may prevent the transfer of knowledge among disciplines involved in cancer research. Leading scientists give insight into mechanisms of carcinogen-induced DNA damage and mutagenicity, and cellular responses including DNA repair, cellular stress, apoptosis, and regulation of cellular growth. Selected human tumor models of oral epithelium, skin cancer, and malignant lymphoma are analyzed in order to determine the most relevant primary genetic alteration in cell-specific transformation. Finally, the epidemiology of p53 mutation is considered as an indication of specific pathogenetic factors in sporadic human tumors.

Table of contents (26 chapters)

Table of contents (26 chapters)
  • Induction of Frameshift Mutations at Hotspot Sequences by Carcinogen Adducts

    Pages 1-20

    Burnouf, D. (et al.)

  • Oxidative DNA Damage Induced by Dioxetanes, Photosensitizing Ketones, and Photo-Fenton Reagents

    Pages 21-34

    Adam, W. (et al.)

  • Oxidative DNA Damage Profiles in Mammalian Cells

    Pages 35-47

    Ballmaier, D. (et al.)

  • Chemical Mechanisms of Formation of DNA-Carcinogen Adducts, Elucidation of Potential of Adducts for Mutagenicity, and Mechanisms of Polymerase Fidelity and Mutation in the Presence of Adducts

    Pages 49-63

    Guengerich, F. P. (et al.)

  • Assessment of the Tumor-Initiating Potential of α,β-Unsaturated Carbonyl Compounds by 32P Postlabeling Quantification of DNA Adducts In Vivo

    Pages 65-75

    Eder, E. (et al.)

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-3-642-60393-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA in USD
  • ISBN 978-3-642-64385-9
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Risk and Progression Factors in Carcinogenesis
Editors
  • H.K. Müller-Hermelink
  • H.G. Neumann
  • W. Dekant
Series Title
Recent Results in Cancer Research
Series Volume
143
Copyright
1997
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-60393-8
DOI
10.1007/978-3-642-60393-8
Softcover ISBN
978-3-642-64385-9
Series ISSN
0080-0015
Edition Number
1
Number of Pages
XII, 394
Topics

*immediately available upon purchase as print book shipments may be delayed due to the COVID-19 crisis. ebook access is temporary and does not include ownership of the ebook. Only valid for books with an ebook version. Springer Reference Works are not included.