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Current Topics in Microbiology and Immunology

Combinatorial Chemistry in Biology

Editors: Famulok, Michael, Winnacker, Ernst-L., Wong, Chi-Huey (Eds.)

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About this book

The essence of combinatorial chemistry or techniques involving "molecular diversity" is to generate enormous populations of molecules and to exploit appropriate screening techniques to isolate active components contained in these libraries. This idea has been the focus of research both in academia and in the pharmaceutical or biotechnology industry. Its developments go hand in hand with an exploding number of potential drug targets emerging from genomics and proteomics research. When the editors of Current Topics in Microbiology and Immunology encouraged us to assemble the present volume on Combinatorial Chemistry in Biology, we immediately felt that this might prove quite beneficial for the audience of this series. The field of combinatorial chemistry extends over a broad range of disciplines, from synthetic organic chemistry to biochemistry, from material sciences to cell biology. Each of these fields may have its own view on this topic, something which is reflected in a growing number of monographs and "special editions" of jour­ nals devoted to this issue or aspects thereof. The title of the present volume of Springer-Verlag's series suggests that it also has its own special focus. And, generally speaking, this is not wrong: we would even claim the special focus of this volume is on the immunologically relevant aspects of combinatorial chemistry.

Table of contents (10 chapters)

Table of contents (10 chapters)
  • Peptide Libraries in Cellular Immune Recognition

    Pages 1-21

    Uebel, S. (et al.)

  • Antigen Sequence- and Library-Based Mapping of Linear and Discontinuous Protein—Protein-Interaction Sites by Spot Synthesis

    Pages 23-36

    Reineke, U. (et al.)

  • The Two Hybrid Toolbox

    Pages 37-54

    Kolanus, W.

  • Evolutionary Approaches to Protein Engineering

    Pages 55-86

    Steipe, B.

  • Phage Display of Combinatorial Peptide and Protein Libraries and Their Applications in Biology and Chemistry

    Pages 87-105

    Johnsson, K. (et al.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-642-60142-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $149.99
price for USA in USD
  • ISBN 978-3-642-64274-6
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Combinatorial Chemistry in Biology
Editors
  • Michael Famulok
  • Ernst-L. Winnacker
  • Chi-Huey Wong
Series Title
Current Topics in Microbiology and Immunology
Series Volume
243
Copyright
1999
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-60142-2
DOI
10.1007/978-3-642-60142-2
Softcover ISBN
978-3-642-64274-6
Series ISSN
0070-217X
Edition Number
1
Number of Pages
IX, 189
Topics

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