Springer Series in Chemical Physics

Fluorescence Correlation Spectroscopy

Theory and Applications

Editors: Rigler, R., Elson, E.S. (Eds.)

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  • First book on this important analytical technique

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  • ISBN 978-3-642-59542-4
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About this book

This book presents the theoretical background to fluorescence correlation spectroscopy (FCS) and a variety of applications in various fields of science. FCS is based on the detection of single molecules excited to fluorescence in diffraction limited confocal volume elements and the time correlation of stochastic events. It provides ultimate sensitivity in the analysis of molecular processes and has found numerous applications in physics, chemistry and particularly in biomolecular sciences. Its high spatial and temporal resolution has made FCS a powerful tool for the analysis of molecular interactions and kinetics, transport properties due to thermal motion and flow, as well as the physics of the excited state in solution as well as at the cellular level. Its application in high throughput drug screening is using all the potential of this prime analytical tool.

Table of contents (22 chapters)

Table of contents (22 chapters)
  • Introduction

    Pages 1-6

    Elson, E.

  • Fluorescence Correlation Spectroscopy of Flavins and Flavoproteins

    Pages 9-24

    Visser, Antonie J. W. G. (et al.)

  • Fluorescence Correlation Spectroscopy in Nucleic Acid Analysis

    Pages 25-64

    Foldes-Pappn, Zeno (et al.)

  • Strain-Dependent Fluorescence Correlation Spectroscopy: Proposing a New Measurement for Conformational Fluctuations of Biological Macromolecules

    Pages 65-83

    Qian, Hong (et al.)

  • Applications of FCS to Protein-Ligand Interactions: Comparison with Fluorescence Polarization

    Pages 84-98

    Matayoshi, Edmund (et al.)

Buy this book

eBook $89.00
price for USA in USD
  • ISBN 978-3-642-59542-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $119.99
price for USA in USD
  • ISBN 978-3-642-64018-6
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Fluorescence Correlation Spectroscopy
Book Subtitle
Theory and Applications
Editors
  • R. Rigler
  • E.S. Elson
Series Title
Springer Series in Chemical Physics
Series Volume
65
Copyright
2001
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg, New York
eBook ISBN
978-3-642-59542-4
DOI
10.1007/978-3-642-59542-4
Softcover ISBN
978-3-642-64018-6
Series ISSN
0172-6218
Edition Number
1
Number of Pages
XX, 487
Topics