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Molecular Biology and Evolution of Blood Group and MHC Antigens in Primates

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  • © 1997

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Table of contents (24 chapters)

  1. Taxonomy and Phylogeny of Primates

  2. Red Blood Cell Antigens

  3. Major Histocompatibility Complex

Keywords

About this book

Zoologists have categorized primates into a single order, and no one doubts today that they share a common ancestry. Humans and Old and New World non­ human primate species, from the lemurs of Madagascar to the African anthro­ poid apes, represent diverging branches of an evolutionary common trunk. Along with species-specific characters, all primates have retained a number of ancestral traits, relics of their common origin. The comparative study of these species-specific and ancestral traits makes it possible to reconstruct the evolu­ tionary pathways of humans and nonhuman primates. The discovery of the human blood groups and, later, of the Major Histocom­ patibility Complex (MHC) had a seminal effect on the field of human genetics, providing the first sound examples of mendel ian polymorphisms. The use of blood group and MHC alleles as genetic markers in biological anthropology gen­ erated a conceptual revolution and persuaded researchers to begin to think in terms of populations and not only intems of typology. The counterparts of these human red and white cell antigens were found and studied in nunhuman primates, and progress in this field is summarized in this book.

Reviews

"The extensive list of references, MHC nucleotide sequences of nonhuman primates, and numerous tables and figures make this a valuable handbook for experts in the field of nonhuman primates. It also provides a comprehensive review of human blood and MHC antigens for clinicians in the fields of hematology, transplantation and transfusion medicine." International Journal of Hematology

Editors and Affiliations

  • Laboratoire d’Immunogénétique moléculaire, Université Paul Sabatier, CHU de Toulouse Hôpital Purpan, Toulouse cedex, France

    Antoine Blancher

  • Max-Planck-Institut für Biologie Abteilung Immungenetik, Tübingen, Germany

    Jan Klein

  • Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, USA

    Jan Klein

  • Laboratory for Experimental Medicine and Surgery in Primates (LEMSIP), New York University Medical Center, Upper Grandview, USA

    Wladyslaw Socha

Bibliographic Information

  • Book Title: Molecular Biology and Evolution of Blood Group and MHC Antigens in Primates

  • Editors: Antoine Blancher, Jan Klein, Wladyslaw Socha

  • DOI: https://doi.org/10.1007/978-3-642-59086-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1997

  • Hardcover ISBN: 978-3-540-61636-8Published: 17 July 1997

  • Softcover ISBN: 978-3-642-63843-5Published: 21 January 2013

  • eBook ISBN: 978-3-642-59086-3Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIV, 570

  • Number of Illustrations: 116 b/w illustrations, 1 illustrations in colour

  • Topics: Immunology, Molecular Medicine

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