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Table of contents (12 papers)
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Front Matter
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Back Matter
About this book
From large cross-sectional studies of autopsy material, it seems as if a time course of Alzheimer's Disease, at least on average, can be mapped out: a pattern of hierarchical vulnerability for neuronal loss and neurofibrillary tangles beginning in medial temporal lobe structures proceeding through association areas. Plaques follow their own temporal course, with widespread cortical deposits occurring even early in a disease process. The whole process may well take twenty years, the first half of which may be without overt symptoms.
Editors and Affiliations
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Neurology Service, Warren 408, Massachusetts General Hospital/Harvard Medical School, Boston, USA
Bradley T. Hyman
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Service Neurologie - Inserm U.455, CHU Hôpital Purpan, Toulouse Cedex 3, France
Jean-François Demonet
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Fondation IPSEN, Pour la Recherche Thérapeutique, Paris Cedex 16, France
Yves Christen
Bibliographic Information
Book Title: The Living Brain and Alzheimer’s Disease
Editors: Bradley T. Hyman, Jean-François Demonet, Yves Christen
Series Title: Research and Perspectives in Alzheimer's Disease
DOI: https://doi.org/10.1007/978-3-642-59300-0
Publisher: Springer Berlin, Heidelberg
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eBook Packages: Springer Book Archive
Copyright Information: Springer-Verlag Berlin Heidelberg 2004
Softcover ISBN: 978-3-642-63927-2Published: 15 April 2014
eBook ISBN: 978-3-642-59300-0Published: 06 December 2012
Series ISSN: 0945-6066
Series E-ISSN: 2196-310X
Edition Number: 1
Number of Pages: XV, 180
Number of Illustrations: 17 b/w illustrations, 33 illustrations in colour
Topics: Neurosciences