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  • Conference proceedings
  • © 1998

Advances in Hematopoietic Stem Cell Transplantation and Molecular Therapy

  • blood stem cell transplantation as therapeutiic option for malignant diseases -gene therapy as alternative treatment- overview of the biology of hematopoietic progentior cells, peripheral stem cell transplantation as well as developments in molecular diagnosis and gene therapeutic concepts.
  • importance of cooperation between basic science and clinical application.

Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 144)

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Table of contents (15 papers)

  1. Front Matter

    Pages I-X
  2. Mobilization and Selection of CD 34+ Cells

    • S. Hohaus, S. Murea, M. T. Voso, R. Haas
    Pages 1-7
  3. Autologous Stem Cell Transplantation for Chronic Myeloid Leukemia

    • F. X. Mahon, G. Marit, J. M. Boiron, P. Cony-Makhoul, P. Agape, A. Pigneux et al.
    Pages 8-14
  4. Peripheral Blood Progenitor Cell Transplantation in Multiple Myeloma Following High-Dose Melphalan-Based Therapy

    • H. Goldschmidt, U. Hegenbart, M. Wallmeier, S. Hohaus, R. Engenhart, M. Wannenmacher et al.
    Pages 27-35
  5. Molecular Monitoring of Residual Disease in Chronic Myelogenous Leukemia Patients After Therapy

    • A. Hochhaus, A. Reiter, H. Skladny, A. Reichert, S. Saußele, R. Hehlmann
    Pages 36-45
  6. Delineation of Genomic Regions in Chromosome Band 7 q22 Commonly Deleted in Myeloid Leukemias

    • K. Fischer, J. Brown, S. W. Scherer, P. Schramm, J. Stewart, G. Fugazza et al.
    Pages 46-52
  7. Molecular Cytogenetic Analysis of Low-Grade B-Cell Neoplasias: a Comparative Genomic Hybridization Study

    • C. A. Werner, H. Döhner, T. F. E. Barth, S. Stilgenbauer, A. Plesch, P. Lichter et al.
    Pages 53-60
  8. Dendritic Cells for Somatic Gene Therapy

    • J. Westermann, A. Aicher, A. Pezzutto
    Pages 70-77
  9. Construction of Immunogenic Tumor Cell Surfaces by Somatic Gene Transfer

    • S. C. Meuer, B. Gückel, M. Lindauer, W. Rudy, U. Moebius
    Pages 78-85
  10. Protection of Hematopoietic Stem Cells from Chemotherapy-Induced Toxicity by Multidrug-Resistance 1 Gene Transfer

    • S. Fruehauf, K. Wermann, E. C. Buss, P. Hundsdoerfer, M. R. Veldwijk, R. Haas et al.
    Pages 93-115
  11. Regulated Gene Expression After Retroviral Vector-Mediated Delivery of Cancer-Relevant Therapeutic Genes

    • W. H. Günzburg, P. Karle, S. Mrochen, G. Sparmann, R. Saller, D. Klein et al.
    Pages 116-126
  12. Back Matter

    Pages 147-150

About this book

Blood stem cell transplantation has become an established therapeutic option in the treatment of malignant diseases. At the same time molecular therapeutic approaches (i.e. gene therapy) are promising alternatives to the classical treatment of cancer. The proceedings give an overview of the biology of hematopoietic progenitor cells, peripheral stem cell transplantation in patients with hematological malignancies, recent developments in molecular diagnosis and gene therapeutic concepts, and show that successful future developments require cooperative research connecting basic science with clinical application.

Authors and Affiliations

  • Klinische Kooperationseinheit Molekulare Hämatologie/Onkologie (460), Deutsches Krebsforschungszentrum, Heidelberg, Germany

    Rainer Haas, Ralf Kronenwett

  • Forschungsschwerpunkt Angewandte Tumorvirologie, Deutsches Krebsforschungszentrum, Heidelberg, Germany

    Georg Sczakiel

Bibliographic Information

  • Book Title: Advances in Hematopoietic Stem Cell Transplantation and Molecular Therapy

  • Authors: Rainer Haas, Ralf Kronenwett, Georg Sczakiel

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-46836-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin · Heidelberg 1998

  • Softcover ISBN: 978-3-642-46838-4Published: 04 April 2012

  • eBook ISBN: 978-3-642-46836-0Published: 06 December 2012

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: X, 150

  • Topics: Oncology, Radiotherapy, Nuclear Medicine

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access