- Wide-ranging coverage of recent evidence on the prevention of prostate cancer, of interest for both clinicians and researchers
- Detailed discussion of risk prediction biomarkers
- Evaluation of the potential role of various means of chemoprevention
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- About this book
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Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5α-reductase inhibitors, DFMO and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.
- Reviews
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From the reviews:
“Part of the Recent Advances in Cancer Research series, this book’s title suggests that it tackles prevention of prostate cancer. … scientists and clinicians who deal with prostate cancer are the main audience. … The discussion of agent development and strategies is very useful to anyone looking to tackle the challenging area of prostate cancer chemoprevention.” (Leonard G. Gomella, Doody’s Book Reviews, May, 2014)
- Table of contents (18 chapters)
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The Biology and Natural History of Prostate Cancer: A Short Introduction
Pages 1-7
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Germline Genetic Variants Associated with Prostate Cancer and Potential Relevance to Clinical Practice
Pages 9-26
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Lifestyle and Dietary Factors in Prostate Cancer Prevention
Pages 27-37
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Nutrition, Hormones and Prostate Cancer Risk: Results from the European Prospective Investigation into Cancer and Nutrition
Pages 39-46
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Screening for Prostate Cancer: Current Status of ERSPC and Screening-Related Issues
Pages 47-51
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Table of contents (18 chapters)
- Download Preface 1 PDF (67.3 KB)
- Download Sample pages 2 PDF (313.4 KB)
- Download Table of contents PDF (104.9 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Prostate Cancer Prevention
- Editors
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- Jack Cuzick
- Mangesh Thorat
- Series Title
- Recent Results in Cancer Research
- Series Volume
- 202
- Copyright
- 2014
- Publisher
- Springer-Verlag Berlin Heidelberg
- Copyright Holder
- Springer-Verlag Berlin Heidelberg
- eBook ISBN
- 978-3-642-45195-9
- DOI
- 10.1007/978-3-642-45195-9
- Hardcover ISBN
- 978-3-642-45194-2
- Softcover ISBN
- 978-3-662-52443-5
- Series ISSN
- 0080-0015
- Edition Number
- 1
- Number of Pages
- VIII, 169
- Number of Illustrations
- 7 b/w illustrations, 4 illustrations in colour
- Topics
