Overview
- A stimulus for the further exploration of the intricate biology of Mycobacterium tuberculosis and its interaction with the host
- Written by respected experts from different disciplines
- Richly illustrated
- Includes supplementary material: sn.pub/extras
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 374)
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Table of contents (9 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Mycobacterium tuberculosis is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of M. tuberculosis as a pathogen is its ability to circumvent host immune responses at different levels. This is not only a result of the special makeup of M. tuberculosis in terms of genetic diversity and DNA metabolism and its possession of specialized secretion systems, but also of its ability to hijack the host’s innate immune defence mechanisms.
In this volume, researchers from different disciplines provide a topical overview of the diverse mechanisms that contribute to the virulence of M. tuberculosis, ranging from their genetic, metabolic and molecular makeup, as well as the complex strategies these bacteria utilize to escape immune destruction within infected hosts.
Editors and Affiliations
Bibliographic Information
Book Title: Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism
Editors: Jean Pieters, John D. McKinney
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-642-40232-6
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2013
Hardcover ISBN: 978-3-642-40231-9Published: 27 December 2013
Softcover ISBN: 978-3-662-52142-7Published: 23 August 2016
eBook ISBN: 978-3-642-40232-6Published: 09 December 2013
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: VIII, 245
Number of Illustrations: 11 b/w illustrations, 11 illustrations in colour
Topics: Medical Microbiology, Immunology, Molecular Medicine, Drug Resistance, Microbial Genetics and Genomics