Nasal Physiology and Pathophysiology of Nasal Disorders

1. Front Matter

   Pages i-xv

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2. Mucus, Goblet Cell, Submucosal Gland

   • Takeshi Shimizu

   Pages 1-14

3. Cilia, Ciliary Movement, and Mucociliary Transport

   • Mark Jorissen, Martine Jaspers

   Pages 15-25

4. Functional Defense Mechanisms of the Nasal Respiratory Epithelium

   • Robert C. Kern, Jennifer R. Decker

   Pages 27-45

5. Local Nasal Inflammation: T Cells and B Cells

   • Els De Schryver, Lien Calus, Lara Derycke, Claus Bachert, Philippe Gevaert

   Pages 47-67

6. Mast Cells

   • Hirohisa Saito

   Pages 69-75

7. Macrophage

   • Hideyuki Kawauchi

   Pages 77-88

8. The Neutrophil and Chronic Rhinosinusitis

   • Martin Y. Desrosiers, Shaun J. Kilty

   Pages 89-93

9. The Role of Eosinophils in Rhinologic Diseases

   • Jens Ponikau, Hirohito Kita, David A. Sherris

   Pages 95-108

10. Nasal NO and Its Role in the Physiology of the Nose and Diagnosis

    • Peter W. Hellings, Glenis K. Scadding

    Pages 109-112

11. Olfaction

    • Caroline Huart, Philippe Eloy, Philippe Rombaux

    Pages 113-137

12. Physiology and Pathophysiology of Sneezing and Itching: Mechanisms of the Symptoms

    • Murat Songu, T. Metin Onerci

    Pages 139-152

13. The Dry Nose

    • Rainer K. Weber, Tanja Hildenbrand, Detlef Brehmer, Jochen A. Werner

    Pages 153-164

14. Physiology of the Aging Nose and Geriatric Rhinitis

    • Victoria E. Varga-Huettner, Jayant M. Pinto

    Pages 165-181

15. Nutrition and the Upper Respiratory Tract

    • James Bartley

    Pages 183-190

16. Nose as a Route for Drug Delivery

    • Ana Serralheiro, Gilberto Alves, Joana Sousa, Ana Fortuna, Amílcar Falcão

    Pages 191-215

17. Physiology of Lacrimal Drainage

    • Ali Riza Cenk Çelebi, T. Metin Önerci

    Pages 217-224

18. Intranasal Trigeminal Perception

    • Philippe Rombaux, Caroline Huart, Basile Landis, Thomas Hummel

    Pages 225-236

19. Sinus Pain

    • James Bartley

    Pages 237-245

20. Computational Fluid Dynamics of the Nasal Cavity

    • Ralph Mösges

    Pages 247-255

Nasal physiology and pathophysiology is a relatively neglected area, yet without a deep knowledge of the physiology it is impossible to understand the impact of structural changes and the process of disease development or to make sound treatment decisions. With the help of numerous tables, schematic drawings, and color photographs, this book will enable the reader to understand the nasal physiology and pathophysiology in detail. All four functions of the nose – respiration, defense, olfaction, and cosmesis  – are covered. Each chapter addresses one important aspect in an accessible way, and each is written by an acknowledged expert on the topic under consideration. The various techniques of clinical evaluation of nasal function are fully discussed, and current trends and future directions in nasal physiologic research are also explored. This book will be of value to both practicing otorhinolaryngologists and novices in the field.​

• Anatomy of the Nose
• Breathing
• Mucosal Immunity
• Nasal Function

• Dept. of Otorhinolaryngology, Hacettepe University Faculty of Medicine, Ankara, Turkey

  T. Metin Önerci

T. Metin Önerci has been Professor of Otorhinolaryngology in the Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Hacettepe University, Ankara, Turkey since 1997, having previously served as Assistant and Associate Professor in the Department. Dr. Önerci has held important positions in a range of medical societies, including President of the International Society of Otorhinolaryngologic Allergy and Immunology (2001-4), General Secretary of the International Rhinologic Society (2005 to the present), President and Honorary President of the Turkish Rhinology Society (since 2000), and President of the European Rhinology Society (2004-6). He is an Associate Editor of Pro Otology and is a member of the editorial boards of several other journals, including Laryngoscope and the International Journal of Rhinology. Dr. Önerci has authored almost 200 papers in national or international journals and many book chapters, and is also the author or editor of 14 books in Turkishand three in English.

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