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Applied Cross-Coupling Reactions

  • Book
  • © 2013

Overview

Editors:
  1. Yasushi Nishihara

    1. Department of Chemistry, Okayama University, Okayama, Japan

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  • The topic of this volume was the subject of the Nobel Prize for Chemistry in 2010
  • Each chapter is written for students by an expert in the field
  • Provides a useful reference for students and teachers of advanced organic chemistry
  • Includes supplementary material: sn.pub/extras

Part of the book series: Lecture Notes in Chemistry (LNC, volume 80)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-x
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  2. Metal-Catalyzed Cross-Coupling Reactions

    1. Front Matter

      Pages 1-1
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    2. A Historic Overview of the Metal-Catalyzed Cross-Coupling Reactions

      • Yasushi Nishihara
      Pages 3-15

    3. Mechanisms and Fundamental Reactions

      • Masayuki Iwasaki, Yasushi Nishihara
      Pages 17-39

  3. Applications of the Cross-Coupling Reactions

    1. Front Matter

      Pages 41-41
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    2. Natural Product Synthesis

      • Yasuhiro Okuda, Yasushi Nishihara
      Pages 43-83

    3. Pharmaceuticals

      • Jiao Jiao, Yasushi Nishihara
      Pages 85-109

    4. Liquid Crystals

      • Ning-Hui Chang, Megumi Kinoshita, Yasushi Nishihara
      Pages 111-135

    5. Conjugated Polymers

      • Daisuke Ogawa, Yasushi Nishihara
      Pages 137-173

  4. Recent Advances in Cross-Coupling Reactions

    1. Front Matter

      Pages 175-175
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    2. Recent Advances in Cross-Coupling Reactions with Aryl Chlorides, Tosylates, and Mesylates

      • Shintaro Noyori, Yasushi Nishihara
      Pages 177-202

    3. Recent Advances in Cross-Coupling Reactions with Alkyl Halides

      • Arisa Yamamoto, Yugo Nishimura, Yasushi Nishihara
      Pages 203-229

  5. Erratum to: A Historic Overview of the Metal-Catalyzed Cross-Coupling Reactions

    • Yasushi Nishihara
    Pages E1-E1

  6. Back Matter

    Pages 231-245
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Keywords

About this book

“Applied Cross-Coupling Reactions” provides students and teachers of advanced organic chemistry with an overview of the history, mechanisms and applications of cross-coupling reactions. Since the discovery of the transition-metal-catalyzed cross-coupling reactions in 1972, numerous synthetic uses and industrial applications have been developed. The mechanistic studies of the cross-coupling reactions have disclosed that three fundamental reactions: oxidative addition, transmetalation, and reductive elimination, are involved in a catalytic cycle. Cross-coupling reactions have allowed us to produce a variety of compounds for industrial purposes, such as natural products, pharmaceuticals, liquid crystals and conjugate polymers for use in electronic devices. Indeed, the Nobel Prize for Chemistry in 2010 was awarded for work on cross-coupling reactions. In this book, the recent trends in cross-coupling reactions are also introduced from the point of view of synthesis design and catalytic activities of transition-metal catalysts.

Editors and Affiliations

  • Department of Chemistry, Okayama University, Okayama, Japan

    Yasushi Nishihara

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