Epigenetic Mechanisms in Cellular Reprogramming
Editors: Meissner, Alexander, Walter, Jörn (Eds.)
Free Preview- Contains translational medicine aspects such as B cell programming and reprogramming in cancer
- Includes extensive glossary
- Understanding stem cell formation is key to develop novel drugs
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- About this book
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The ability of a single genome to give rise to hundreds of functionally distinct cell type programs is in itself remarkable. Pioneering studies over the past few decades have demonstrated that this plasticity is retained throughout development, a phenomenon of epigenetic programming and reprogramming that remains one of the most fascinating areas of modern biology, with major relevance to human health and disease. This book presents the basic biology involved, including key mechanistic insights into this rapidly growing field.
- Table of contents (9 chapters)
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The Oocyte Determinants of Early Reprogramming
Pages 1-29
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Stella and Zygotic Reprogramming
Pages 31-42
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Histone Variants and Reprogramming in Early Development
Pages 43-68
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DNA Methylation Reprogramming in Preimplantation Development
Pages 69-99
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Establishing and Maintaining Pluripotency: An Epigenetic Perspective
Pages 101-120
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Table of contents (9 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Epigenetic Mechanisms in Cellular Reprogramming
- Editors
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- Alexander Meissner
- Jörn Walter
- Series Title
- Epigenetics and Human Health
- Copyright
- 2015
- Publisher
- Springer-Verlag Berlin Heidelberg
- Copyright Holder
- Springer-Verlag Berlin Heidelberg
- eBook ISBN
- 978-3-642-31974-7
- DOI
- 10.1007/978-3-642-31974-7
- Hardcover ISBN
- 978-3-642-31973-0
- Softcover ISBN
- 978-3-662-51062-9
- Series ISSN
- 2191-2262
- Edition Number
- 1
- Number of Pages
- XVIII, 230
- Number of Illustrations
- 1 b/w illustrations, 19 illustrations in colour
- Topics
