Behavioral Neurogenetics

1. Front Matter

   Pages i-xi

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2. Using Zebrafish to Unravel the Genetics of Complex Brain Disorders

   • Robert Gerlai

   Pages 3-24

3. Forward Genetic Approaches to Understanding Complex Behaviors

   • Lisa M. Tarantino, Amy F. Eisener-Dorman

   Pages 25-58

4. Mouse Models of the 5-HTTLPR × Stress Risk Factor for Depression

   • Valeria Carola, Cornelius Gross

   Pages 59-72

5. Behavioral and Pharmacogenetics of Aggressive Behavior

   • Aki Takahashi, Isabel M. Quadros, Rosa M. M. de Almeida, Klaus A. Miczek

   Pages 73-138

6. Selectively Bred Rodents as Models of Depression and Anxiety

   • Gregers Wegener, Aleksander A. Mathe, Inga D. Neumann

   Pages 139-187

7. Stress-Induced Deficits in Cognition and Emotionality: A Role for Glutamate

   • Carolyn Graybeal, Carly Kiselycznyk, Andrew Holmes

   Pages 189-207

8. Susceptibility Genes for Schizophrenia: Mutant Models, Endophenotypes and Psychobiology

   • Colm M. P. O’Tuathaigh, Lieve Desbonnet, Paula M. Moran, John L. Waddington

   Pages 209-250

9. Genetic Models of Sensorimotor Gating: Relevance to Neuropsychiatric Disorders

   • Susan B. Powell, Martin Weber, Mark A. Geyer

   Pages 251-318

10. Applications of Second Generation Sequencing Technologies in Complex Disorders

    • Mònica Bayés, Simon Heath, Ivo Glynne Gut

    Pages 321-343

11. Rare Genomic Deletions and Duplications and their Role in Neurodevelopmental Disorders

    • Joseph T. Glessner, John J.M. Connolly, Hakon Hakonarson

    Pages 345-360

12. Toward a Mechanistic Understanding of How Variability in Neurobiology Shapes Individual Differences in Behavior

    • Ryan Bogdan, Justin M. Carré, Ahmad R. Hariri

    Pages 361-393

13. Behavioural Genetics of Childhood Disorders

    • Christine M. Freitag, Philip Asherson, Johannes Hebebrand

    Pages 395-428

14. Schizophrenia Genes: On the Matter of Their Convergence

    • Dan Rujescu

    Pages 429-440

15. Gene × Environment Interaction Models in Psychiatric Genetics

    • Katja Karg, Srijan Sen

    Pages 441-462

16. Behavioral Genetics of Affective and Anxiety Disorders

    • Katharina Domschke, Andreas Reif

    Pages 463-502

17. Behavioural Genetics of the Serotonin Transporter

    • K. Haddley, V. J. Bubb, G. Breen, U. M. Parades-Esquivel, J. P. Quinn

    Pages 503-535

18. Genetic Factors Modulating the Response to Stimulant Drugs in Humans

    • Amy B. Hart, Harriet de Wit, Abraham A. Palmer

    Pages 537-577

19. The Cognitive Genetics of Neuropsychiatric Disorders

    • A. Corvin, G. Donohoe, A. Hargreaves, L. Gallagher, M. Gill

    Pages 579-613

20. Behavioral Genetics of Neurodegenerative Disorders

    • Daniela Galimberti, Elio Scarpini

    Pages 615-631

This book covers a wide array of topics relevant to behavioral genetics from both a preclinical and clinical standpoint. Indeed in juxtaposing both areas of research the reader will appreciate the true translational nature of the field. Topics covered range from technical advances in genetic analysis in humans and animals to specific descriptions of advances in schizophrenia, attention disorders, depression and anxiety disorders, autism, aggression, neurodegeneration and neurodevelopmental disorders. The importance of gene-environment interactions is emphasised and the role of neuroimaging in unravelling the functional consequences of genetic variability described. This volume will be valued by both the basic scientist and clinician alike who may use it as a detailed reference book. It will also be of use to the novice to the field, to whom it will serve as an in-depth introduction to this exciting area of research.

• behavioral disorders
• behavioral genetics
• neurodegenerative disorders
• neurodevelopmental disorders
• neurogenetics

• , Dep of Pharmacology and Therapeutics, School of Pharmacy, Cork, Ireland

  John F. Cryan

• , Department of Psychiatry and Psychothera, University of Würzburg, Würzburg, Germany

  Andreas Reif

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