Save today: Get 40% off titles in Popular Science!

Regulatory RNAs

Basics, Methods and Applications

Editors: Mallick, Bibekanand, Ghosh, Zhumur (Eds.)

Free Preview
  • Complete overview on regulatory RNAs
  • Includes the basics, methods and applicative areas involving these regulatory RNAs
  • Written by international experts
see more benefits

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-3-642-22517-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
Softcover $199.99
price for USA in USD
About this book

Recent progress in high-throughput technologies and genome wide transcriptome studies have lead to a significant scientific milestone of discovering non-coding RNAs (ncRNAs) which spans through a major portion of the genome. These RNAs most often act as riboregulators, and actively participate in the regulation of important cellular functions at the transcriptional and/or post-transcriptional levels rather than simply being an intermediated messenger between DNA and proteins. As the appreciation for the importance of ncRNAs continues to emerge, it is also increasingly clear that these play critical roles in gene regulatory processes during development and differentiation. Further, regulatory RNAs are useful biomarkers for diagnosis of diseases. Hence these RNA regulators are essential to the development of therapeutics. This book on “Regulatory RNAs” offers a comprehensive view on our current understanding of these regulatory RNAs viz. siRNA, miRNA, piRNA, snoRNA, long non-coding RNA, small RNA etc. It addresses both the biogenesis and mechanism of action of regulatory RNAs with a primary focus on their annotation, experimental methodologies (microarray, next-gen sequencing etc.) for their discovery, computational tools for their prediction, and above all, applications of these revolutionary regulatory molecules in understanding biological systems and diseases, including therapeutics. This comprehensive volume is intended for readers with research or teaching interests in ncRNA biology and will provide a major information resource on current research in the fast-moving fields of RNA and gene expression regulation. Cutting-edge and concise, “Regulatory RNAs: Basics, Methods and Applications” promises to support vital research in the field of regulatory RNAs, ever-continuing to grow rapidly and gain increasing importance in basic and translational biology.

Reviews

From the reviews:

“The book represents a valuable collection of articles that reflect the current knowledge in the RNAi field. It is useful for both biologists and bioinformaticians, researchers and students alike, and strengthens the links between molecular biology and bioinformatics.” (Irina Ioana Mohorianu, zbMATH, Vol. 1275, 2014)

Table of contents (21 chapters)

Table of contents (21 chapters)
  • Renaissance of the Regulatory RNAs

    Pages 3-22

    Ghosh, Zhumur (et al.)

  • Diversity, Overlap, and Relationships in the Small RNA Landscape

    Pages 23-48

    Scott, Michelle S.

  • Fragments of Small Nucleolar RNAs as a New Source for Noncoding RNAs

    Pages 49-71

    Falaleeva, Marina (et al.)

  • Small Regulatory RNAs (sRNAs): Key Players in Prokaryotic Metabolism, Stress Response, and Virulence

    Pages 73-109

    Brantl, Sabine

  • The Canonical RNA Interference Pathway in Animals

    Pages 111-149

    Nejepinska, Jana (et al.)

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-3-642-22517-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
Softcover $199.99
price for USA in USD
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Regulatory RNAs
Book Subtitle
Basics, Methods and Applications
Editors
  • Bibekanand Mallick
  • Zhumur Ghosh
Copyright
2012
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-22517-8
DOI
10.1007/978-3-642-22517-8
Hardcover ISBN
978-3-642-22516-1
Softcover ISBN
978-3-642-44284-1
Edition Number
1
Number of Pages
X, 554
Topics