Overview
- Editors:
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Meital Zilberman
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Fac. Engineering, Dept. Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel
- Gives a broad overview of biomaterial platforms for drug-eluting implants
- Presents new approaches for creating clinically important biomedical applications
- Describes both, internal and external implants
- Includes supplementary material: sn.pub/extras
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Table of contents (18 chapters)
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- Jonathan J. Elsner, Israela Berdicevsky, Adaya Shefy-Peleg, Meital Zilberman
Pages 3-37
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- Boaz Mizrahi, Christopher Weldon, Daniel S. Kohane
Pages 39-56
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- Mădălina V. Natu, HermÃnio C. de Sousa, Maria H. Gil
Pages 57-85
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- Dennis Douroumis, Ichioma Onyesom
Pages 87-125
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- Mikael Trollsas, Bozena Maslanka, Nam Pham, Qing Lin, Syed Hossainy, Shaw Ling Hsu et al.
Pages 127-143
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- Morten Østergaard Andersen, Jørgen Kjems
Pages 145-165
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- John Igwe, Ami Amini, Paiyz Mikael, Cato Laurencin, Syam Nukavarapu
Pages 169-192
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- Aysen Tezcaner, Dilek Keskin
Pages 193-223
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- Irena Gotman, Sabine Fuchs
Pages 225-258
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- Rossella Dorati, Claudia Colonna, Ida Genta, Bice Conti
Pages 259-285
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- Emil Ruvinov, Smadar Cohen
Pages 289-328
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- Dae-Duk Kim, Dong-Hwan Kim, Yun-Jeong Son
Pages 329-349
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- Marta Roldo, Dimitrios G. Fatouros
Pages 351-376
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- Ali Demir Sezer, Erdal Cevher
Pages 377-406
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- Jukka Seppälä, Harri Korhonen, Risto Hakala, Minna Malin
Pages 409-438
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- Maya Davidovich-Pinhas, Havazelet Bianco-Peled
Pages 439-456
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- Yu Tang, Mayura Oak, Rhishikesh Mandke, Buddhadev Layek, Gitanjali Sharma, Jagdish Singh
Pages 457-479
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- Darren Svirskis, Bryon E. Wright, Jadranka Travas-Sejdic, Sanjay Garg
Pages 481-512
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Back Matter
Pages 513-514
About this book
Active implants are actually drug or protein-eluting implants that induce healing effects, in addition to their regular task, such as support. This effect is achieved by controlled release of the active agent to the surrounding tissue. This book will give a broad overview of biomaterial platforms used as basic elements of drug-eluting implants. It will include mainly coatings for vascular stents with controlled release of antiproliferative agents, wound dressings with controlled release of antibacterial agents, drug-eluting vascular grafts, protein-eluting scaffolds for tissue regeneration, drug-eluting platforms for dental and other applications. Thus, both internal and external implants are described. The drug-eluting implants will be described in terms of matrix formats and polymers, incorporated drugs and their release profiles from the implants, as well as implant functioning. Smart polymeric systems, such as crosslinked poly-lactones, thermo and pH-sensitive hydrogels and poly(amido-amines), as well as novel basic structural elements, such as composite fibers and films, and nanostructures will be thoroughly described. The effect of the processing parameters on the microstructure and on the resulting drug release profiles, mechanical and physical properties, and other relevant properties, will be emphasized. The described new biomaterials approaches for active implants enhance the tools available for creating clinically important biomedical applications.
Editors and Affiliations
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Fac. Engineering, Dept. Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel
Meital Zilberman
