Current Topics in Microbiology and Immunology

Small-Molecule Inhibitors of Protein-Protein Interactions

Editors: Vassilev, Lyubomir, Fry, David (Eds.)

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  • Features knowledgeable insights from a number of leaders in this field. The content of the articles is rich, and in terms of scope ranges from generalized approaches to specific case studies. 
  • There are numerous lessons to be taken away from this collection, and the authors hope that this snapshot of the current state of the art in developing  protein-protein inhibitors not only pays tribute to the past successes, but also generates excitement about the future potential of this field.   
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About this book

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In this volume, the editors have collected the knowledgeable insights of a number of leaders in this field - researchers who have achieved success in addressing the difficult problem of inhibiting protein-protein interactions. These researchers describe their unique approaches, and share experiences, results, thoughts, and opinions. The content of the articles is rich, and in terms of scope ranges from generalized approaches to specific case studies. There are various focal points, including methodologies and the molecules themselves. Ultimately, there are numerous lessons to be taken away from this collection, and the editors hope that this snapshot of the current state of the art in developing protein-protein inhibitors not only pays tribute to the past successes, but also generates excitement about the future potential of this field.

Table of contents (7 chapters)

Table of contents (7 chapters)
  • Hydrogen-Bonded Synthetic Mimics of Protein Secondary Structure as Disruptors of Protein-Protein Interactions

    Adler, Marc J. (et al.)

    Pages 1-23

  • Small-Molecule Inhibitors of IL-2/IL-2R: Lessons Learned and Applied

    Wilson, C. G. M. (et al.)

    Pages 25-59

  • Small Molecule Inhibitors of the Human Papillomavirus E1-E2 Interaction

    White, Peter W. (et al.)

    Pages 61-88

  • Design of Small-Molecule Smac Mimetics as IAP Antagonists

    Wang, Shaomeng

    Pages 89-113

  • Small-Molecule Inhibitors Reveal a New Function for Bcl-2 as a Proangiogenic Signaling Molecule

    Zeitlin, Benjamin D. (et al.)

    Pages 115-137

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-3-642-17083-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-3-642-17082-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.99
price for USA in USD
  • ISBN 978-3-642-26670-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Small-Molecule Inhibitors of Protein-Protein Interactions
Editors
  • Lyubomir Vassilev
  • David Fry
Series Title
Current Topics in Microbiology and Immunology
Series Volume
348
Copyright
2011
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-17083-6
DOI
10.1007/978-3-642-17083-6
Hardcover ISBN
978-3-642-17082-9
Softcover ISBN
978-3-642-26670-6
Series ISSN
0070-217X
Edition Number
1
Number of Pages
X, 174
Topics