Combating Fungal Infections

Problems and Remedy

Editors: Ahmad, I., Owais, M., Shahid, M., Aqil, F. (Eds.)

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  • Provides an overall comprehensive holistic approach to combating fungal infections
  • Presents recent research developments to aid fighting fungal infections
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eBook $219.00
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  • ISBN 978-3-642-12173-9
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Hardcover $299.99
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  • ISBN 978-3-642-12172-2
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Softcover $279.99
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  • ISBN 978-3-642-44672-6
  • Free shipping for individuals worldwide
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About this book

The currently available means of combating fungal infections are still weak and clumsy. The application of fungal genomics offers an unparalleled opportunity to develop novel antifungal drugs. Interestingly, several novel antifungal drug targets have already been identified and validated. However, it is too early to expect any novel antifungal drug as drug discovery programs are still in their infancy. In addition to classical and genomic approaches to drug discovery, traditional knowledge derived from natural products and phytomedicine can provide a multitude of alternative modes of combating fungal infection. This book comprises 20 chapters on various aspects pertaining to fungal diseases in human and animals, their reservoir, fungal pathogenesis, their management and recent advances in their treatment. Issues of antifungal drug toxicity, especially nephrotoxicity, are also discussed. The development of resistance in fungal pathogens, including multidrug resistance and its mechanism, is dealt with in two chapters. Diverse diagnostic approaches to fungal infections are also reviewed. The combinational drug strategies used in combating invasive fungal infections are addressed in detail. The management of pulmonary mycoses in stem cell transplantation is also given special focus. Novel antifungal drugs (synthetic and herbal), fungal vaccines, and metabolic pathways as drug targets are discussed in detail in three different chapters. Subsequently the roles of innate immunity, cytokine therapy and immunomodulators in the treatment of fungal infections are elaborated upon. As novel drug delivery systems have a great potential for modifying the pharmacokinetics of medications, the last chapter takes this fact into consideration in its examination of state-of-the-art delivery systems in controlling fungal infections.

Table of contents (20 chapters)

Table of contents (20 chapters)
  • Mould Infections: A Global Threat to Immunocompromised Patients

    Araujo, Ricardo (et al.)

    Pages 1-19

  • Virulence and Pathogenicity of Fungal Pathogens with Special Reference to Candida albicans

    Khan, Mohd Sajjad Ahmad (et al.)

    Pages 21-45

  • Animal as Reservoir of Fungal Diseases (Zoonoses?)

    Blanco, Jose L. (et al.)

    Pages 47-70

  • Fungi Associated with Eye Infections with Special Reference to Corneal Keratitis and Their Possible Reservoir

    Ahmad, Shamim (et al.)

    Pages 71-97

  • Antifungal Drugs Mode of Action and Recent Development

    Sakagami, Yoshikazu

    Pages 99-107

Buy this book

eBook $219.00
price for USA in USD (gross)
  • ISBN 978-3-642-12173-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.99
price for USA in USD
  • ISBN 978-3-642-12172-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.99
price for USA in USD
  • ISBN 978-3-642-44672-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Combating Fungal Infections
Book Subtitle
Problems and Remedy
Editors
  • Iqbal Ahmad
  • Mohammad Owais
  • Mohammed Shahid
  • Farrukh Aqil
Copyright
2010
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-12173-9
DOI
10.1007/978-3-642-12173-9
Hardcover ISBN
978-3-642-12172-2
Softcover ISBN
978-3-642-44672-6
Edition Number
1
Number of Pages
XX, 539
Topics