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Current Topics in Microbiology and Immunology

Dengue Virus

Editors: Rothman, Alan L. (Ed.)

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About this book

Scientific research on dengue has a long and rich history. The literature has been touched by famous names in medicine- Benjamin Rush, Walter Reed, and Albert Sabin, to name a very few- and has been fertile ground for medical historians . The advances made in those early investigations are all the more remarkable for the limited tools available at the time. The demonstration of a viral etiology for dengue fever, the recognition of mosquitoes as the vector for transmission to humans, and the existence of multiple viral variants (serotypes) with only partial cross-protection were all accomplished prior to the ability to culture and characterize the etiologic agent. Research on dengue in this period was typically driven by circumstances. Epidemics of dengue created public health crises, although these were relatively short-lived in any one location, as the population of susceptible individuals quickly shrank. Military considerations became as a major driving force for research. With the introduction of large numbers of non-immune individuals into endemic areas, dengue could cripple military readiness, taking more soldiers out of action than hostile fire. Dengue and dengue hemorrhagic fever, which assumed pandemic proportions during the latter half of the last century, have shown no indication of slowing their growth during this first decade of the twenty-first century. Challenges remain in understanding the basic mechanisms of viral replication and disease pathogenesis, in clinical management of patients, and in control of dengue viral transmission. Nevertheless, new tools and insights have led to major recent scientific advances. As the first candidate vaccines enter large-scale efficacy trials, there is reason to hope that we may soon "turn the corner" on this disease.

Table of contents (11 chapters)

Table of contents (11 chapters)
  • Prospective Cohort Studies of Dengue Viral Transmission and Severity of Disease

    Pages 1-13

    Endy, Timothy P. (et al.)

  • Control of Dengue Virus Translation and Replication

    Pages 15-34

    Paranjape, Suman M. (et al.)

  • Subversion of Interferon by Dengue Virus

    Pages 35-44

    Muñoz-Jordán, Jorge L.

  • Dengue Virus Virulence and Transmission Determinants

    Pages 45-55

    Rico-Hesse, R.

  • Systemic Vascular Leakage Associated with Dengue Infections – The Clinical Perspective

    Pages 57-66

    Trung, Dinh T. (et al.)

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-3-642-02215-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-3-642-02214-2
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
Softcover $219.99
price for USA in USD
  • ISBN 978-3-642-26088-9
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Dengue Virus
Editors
  • Alan L. Rothman
Series Title
Current Topics in Microbiology and Immunology
Series Volume
338
Copyright
2010
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
Distribution Rights
Distribution rights for India: CBS Publishers, New Delhi, India
eBook ISBN
978-3-642-02215-9
DOI
10.1007/978-3-642-02215-9
Hardcover ISBN
978-3-642-02214-2
Softcover ISBN
978-3-642-26088-9
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XV, 161
Number of Illustrations
9 illustrations in colour
Topics

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