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  • © 2008

Primary Immunodeficiency Diseases

Definition, Diagnosis, and Management

  • Truly international
  • Interdisciplinary
  • Includes supplementary material: sn.pub/extras

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Table of contents (11 chapters)

  1. Front Matter

    Pages I-XXVIII
  2. An Introduction to Primary Immunodeficiency Diseases

    • Nima Rezaei, Francisco A. Bonilla, Kathleen E. Sullivan, Esther de Vries, Jordan S. Orange
    Pages 1-38
  3. Combined T and B Cell Immunodeficiencies

    • Françoise Le Deist, Despina Moshous, Steven J. Howe, Amit Nahum, Fotini D. Kavadas, Elana Lavine et al.
    Pages 39-95
  4. Predominantly Antibody Deficiencies

    • Asghar Aghamohmmadi, Vassilios Lougaris, Alessandro Plebani, Toshio Miyawaki, Anne Durandy, Lennart Hammarström
    Pages 97-130
  5. Phagocytes Defects

    • Uwe Wintergerst, Sergio D. Rosenzweig, Mario Abinun, Harry L. Malech, Steven M. Holland, Nima Rezaei
    Pages 131-166
  6. Genetic Disorders of Immune Regulation

    • Carsten Speckmann, Jan Rohr, Stephan Ehl
    Pages 167-194
  7. Defects in Innate Immunity: Receptors and Signaling Components

    • Nima Parvaneh, Joachim Roesler, Steven M. Holland, Tim Niehues
    Pages 195-214
  8. Autoinflammatory Disorders

    • Stefan Berg, Anders Fasth
    Pages 215-233
  9. Complement Deficiencies

    • Maryam Mahmoudi, Tom Eirik Mollnes, Taco W. Kuijpers, Dirk Roos
    Pages 235-249
  10. Other Well-Defined Immunodeficiencies

    • Mehdi Yeganeh, Eleonora Gambineri, Kamran Abolmaali, Banafshe Tamizifar, Teresa Español
    Pages 251-290
  11. Syndromic Immunodeficiencies

    • Jeffrey E. Ming, E. Richard Stiehm
    Pages 291-314
  12. Treatment of Primary Immunodeficiency Diseases

    • Hale Yarmohammadi, Charlotte Cunningham-Rundles
    Pages 315-334
  13. Back Matter

    Pages 335-358

About this book

Primary immunodeficiency diseases (PID) are a group of disorders involving defects in one or more components of the immune system, and are characterized by an increased incidence of infections, autoimmunity, and malignancies. Although PID seem to be rare, the number of patients diagnosed has increased in recent years, and more than 150 different forms of PID have been identified. Nevertheless, because of inadequate medical awareness, a significant number of patients with PID are either not recognized as having a PID or are not diagnosed as early as they should be. Such delays lead to a substantial increase in morbidity and mortality among affected individuals.
Our understanding of PID is improving rapidly, which will hopefully lead to more accurate diagnosis and efficient disease management. This book contains the most recent advances in the field, as well as a concise and structured review of previously identified PID. Although the book’s primary focus is on practical diagnosis and management, the pathophysiology of PID is also discussed.
This book is a comprehensive yet manageable resource for physicians and nurses wishing to learn more about PID, as well as a useful tool for both doctors-in-training and specialists in clinical decision-making and treatment planning.

Reviews

From the reviews:

"This is a great book. … The book is written by a number of well recognised authors who are experts in their field and there is international representation. … The chapters are well-written and up-to-date. … The book is punctuated throughout with very good colour clinical photographs that help bring out some of the salient points in the text, and are to be recommended. … an excellent book and there should be at least one copy in every immunology department, university and hospital library." (Andrew Gennery, Immunology News, May, 2009)

"It provides a useful and easy-to-read update, covering most of the disorders associated with defects in lymphocytes, phagocytes, and complement. … This will be informative for health planners. … Clinicians … will inevitably follow the many citations at the end of each chapter. … immunologists and specialist nurses managing the care of patients with primary immunodeficiency diseases should have this text on their shelves, as should general pediatric departments and hospital medical libraries. The book will likewise be of interest to scientists … ." (A. D. B. Webster, Journal of the American Medical Association, Vol. 302 (9), September, 2009)

Editors and Affiliations

  • Immunology, Asthma and Allergy Research Institute Children’s Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran

    Nima Rezaei

  • Section of Infection, Inflammation and Immunity School of Medicine and Biomedical Sciences, The University of Sheffield, Sheffield, UK

    Nima Rezaei

  • Division of Allergy and Clinical Immunology Children’s Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran

    Asghar Aghamohammadi

  • Division of Immunology Children’s Hospital, Harvard Medical School, Boston, USA

    Luigi D. Notarangelo

Bibliographic Information

  • Book Title: Primary Immunodeficiency Diseases

  • Book Subtitle: Definition, Diagnosis, and Management

  • Editors: Nima Rezaei, Asghar Aghamohammadi, Luigi D. Notarangelo

  • DOI: https://doi.org/10.1007/978-3-540-78936-9

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2008

  • eBook ISBN: 978-3-540-78936-9Published: 06 August 2008

  • Edition Number: 1

  • Number of Pages: XXVIII, 358

  • Topics: Pediatrics, Immunology, Infectious Diseases, Allergology, Internal Medicine, Human Genetics

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Other ways to access