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Angiogenesis Inhibition

  • Book
  • © 2010

Overview

Editors:
  1. Rüdiger Liersch

    1. Medizinische Klinik und Poliklinik A, Universitätsklinikum Münster, Münster, Germany

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  2. Wolfgang E. Berdel

    1. Medizinische Klinik und Poliklinik, Universitätsklinikum Münster, Münster, Germany

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  3. Torsten Kessler

    1. Medizinische Klinik und Poliklinik A, Universitätsklinikum Münster, Münster, Germany

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  • A general overview of the latest developments in angiogenesis inhibition in cancer
  • Considers all aspects from the bench to the bedside, with detailed attention both to basic research and to its translation into clinical practice
  • Presents the latest results of clinical trials
  • Discusses various advanced targeting strategies

Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 180)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xiv
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  2. Introduction

    • Rüdiger Liersch, Wolfgang E. Berdel, Torsten Kessler
    Pages 1-1

  3. Angiopoietins

    • Yvonne Reiss
    Pages 3-13

  4. HIF-1α and Cancer Therapy

    • Mei Yee Koh, Taly R. Spivak-Kroizman, Garth Powis
    Pages 15-34

  5. Chemokines

    • Andreas Hippe, Bernhard Homey, Anja Mueller-Homey
    Pages 35-50

  6. Angiogenesis Inhibition in Cancer Therapy

    • Iris Appelmann, Rüediger Liersch, Torsten Kessler, Rolf M. Mesters, Wolfgang E. Berdel
    Pages 51-81

  7. Vascular Integrins: Therapeutic and Imaging Targets of Tumor Angiogenesis

    • Curzio Rüegg, Gian Carlo Alghisi
    Pages 83-101

  8. PDGF and Vessel Maturation

    • Carina Hellberg, Arne Östman, C.-H. Heldin
    Pages 103-114

  9. Lymphangiogenesis in Cancer: Current Perspectives

    • Rüediger Liersch, Christoph Biermann, Rolf M. Mesters, Wolfgang E. Berdel
    Pages 115-135

  10. Compounds in Clinical Phase III and Beyond

    • Torsten Kessler, Michael Bayer, Christian Schwöppe, Rüdiger Liersch, Rolf M. Mesters, Wolfgang E. Berdel
    Pages 137-163

  11. Metronomic Chemotherapy: Principles and Lessons Learned from Applications in the Treatment of Metastatic Prostate Cancer

    • Urban Emmenegger, Giulio Francia, Yuval Shaked, Robert S. Kerbel
    Pages 165-183

  12. Targeting Inflammatory Cells to Improve Anti-VEGF Therapies in Oncology

    • Hans-Peter Gerber, Ezogelin Olazoglu, Iqbal S. Grewal
    Pages 185-200

  13. Antibody-Based Vascular Tumor Targeting

    • Christoph Schliemann, Dario Neri
    Pages 201-216

  14. Caveolae and Cancer

    • Kerri A. Massey, Jan E. Schnitzer
    Pages 217-231
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Keywords

About this book

Angiogenesis is attracting increased scientific and clinical interest. The identification of novel mediators and targeting molecules has led to significant progress in our understanding of tumor angiogenesis and tumor vessel targeting. Important advances in cancer treatment have already emerged, and in the future, blood vessel targeting will play a significant role within individualized therapeutic strategies. This volume provides a general overview of the latest developments in angiogenesis inhibition in cancer. All aspects from the bench to the bedside are considered, with detailed attention both to basic research and to its translation into clinical practice. Individual chapters are devoted to the roles of angiopoietins, HIF-1a, chemokines, PDGF and VEGF, and vascular integrins. The latest results of clinical trials are presented, and various advanced targeting strategies are discussed. This book will be invaluable to all who wish to learn of the most recent advances in this exciting field.

Editors and Affiliations

  • Medizinische Klinik und Poliklinik A, Universitätsklinikum Münster, Münster, Germany

    Rüdiger Liersch, Torsten Kessler

  • Medizinische Klinik und Poliklinik, Universitätsklinikum Münster, Münster, Germany

    Wolfgang E. Berdel

Bibliographic Information

  • Book Title: Angiogenesis Inhibition

  • Editors: Rüdiger Liersch, Wolfgang E. Berdel, Torsten Kessler

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-540-78281-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2010

  • Hardcover ISBN: 978-3-540-78280-3Published: 19 November 2009

  • Softcover ISBN: 978-3-642-26143-5Published: 05 May 2012

  • eBook ISBN: 978-3-540-78281-0Published: 24 December 2009

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: XIV, 231

  • Topics: Oncology, Hematology, Cancer Research

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