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Topics in Organometallic Chemistry

Directed Metallation

Editors: Chatani, Naoto (Ed.)

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  • Provides the broad scientific readership with comprehensive summary and critical overview of a topic in organometallic chemistry
  • Research in this rapidly developing transdisciplinary field is having profound influence on other areas of scientific investigation, ranging from catalytic organic synthesis to biology, medicine, and material science
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  • ISBN 978-3-540-75809-9
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Hardcover $349.99
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Softcover $349.99
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About this book

Directed metalation is recognized as one of the most useful methodologies for the regio- and stereoselective generation of organometallic species, the generation of which necessarily leads to the selective formation of organic products. Cyclometalation using Li, Mn, and Pd, and directed hydrometalation and carbometalation using Al and Zn, have been utilized for regio- and/or stereoselective synthesis for decades. Recently, a new chelation-assisted methodology has been developed not only for controlling regio- and stereoselectivity of reactions, but also for accelerating reactions. In particular, chelation-methodology has been utilized as a new activation method, in which a carbon-metal bond is generated directly from a C-H bond; a reaction rarely achieved using conventional methods. A wide variety of catalytic functionalization reactions of C-H bonds by the utilization of a chelation, have been developed recently and are comprehensively discussed in this book by leading experts. In addition, new approaches to directed hydrometalation and directed carbometalation as a key step are also discussed. A unique stereo- and regioselective hydroformylation has been developed through the utilization of directed hydrometalation. The regioselective Mizoroki-Heck reaction is another example in which directed carbometalation can be used to achieve a high regioselectivity. These examples emphasize how these innovative methodologies are contributing to different fields of chemistry.

Reviews

From the reviews:

"This volume provides summaries of transition metal catalyzed reactions where a directed metalation is involved. … Chatani has compiled seven reviews that are written by experts in the field, are heavily referenced, and are amply illustrated. This work also contains a subject index for this volume and an author index for all 24 volumes in the series. Summing Up: Recommended. Graduate students through professionals." (J. Landesberg, CHOICE, Vol. 45 (10), June, 2008)


Table of contents (7 chapters)

Table of contents (7 chapters)
  • Catalytic Addition of C – H Bonds to C – C Multiple Bonds

    Pages 1-33

    Kakiuchi, Fumitoshi

  • Chelation-Assisted Arylation via C–H Bond Cleavage

    Pages 35-60

    Ackermann, Lutz

  • Catalytic Arylation and Vinylation Reactions Directed by Anionic Oxygen Functions via Cleavage of C – H and C – C Bonds

    Pages 61-84

    Satoh, Tetsuya (et al.)

  • Chelate-Directed Oxidative Functionalization of Carbon–Hydrogen Bonds: Synthetic Applications and Mechanistic Insights

    Pages 85-116

    Kalyani, Dipannita (et al.)

  • Directed C – C Bond Activation by Transition Metal Complexes

    Pages 117-143

    Jun, Chul-Ho (et al.)

Buy this book

eBook $269.00
price for USA in USD
  • ISBN 978-3-540-75809-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $349.99
price for USA in USD
Softcover $349.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Directed Metallation
Editors
  • Naoto Chatani
Series Title
Topics in Organometallic Chemistry
Series Volume
24
Copyright
2007
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-75809-9
DOI
10.1007/978-3-540-75809-9
Hardcover ISBN
978-3-540-75808-2
Softcover ISBN
978-3-642-09493-4
Series ISSN
1436-6002
Edition Number
1
Number of Pages
XII, 206
Number of Illustrations
170 b/w illustrations
Topics