Current Topics in Microbiology and Immunology

Specialization and Complementation of Humoral Immune Responses to Infection

Editors: Manser, Tim (Ed.)

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  • Highlights a new perspective on antibody responses to infection
  • Conveys its practical implications
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About this book

In recent years the results of past studies on T cell dependent and T cell independent antibody responses have coalesced with discoveries regarding the roles of various primary B cell subsets and components of the innate immune system in conferring resistance to infectious pathogens. As a consequence, a new and more complete understanding of how antibody-mediated resistance to pathogens is elaborated has emerged. The recent explosion of knowledge of Toll-like receptor specificity and function has further embellished this understanding. It is now clear that there is not only extensive overlap and cross-complementarity in the action of innate and adaptive immune systems, but also specialization of function of the various B cell subsets and the types of antibodies they produce. This synergistic interaction of multiple components of these systems is perhaps best exemplified in antibody responses to bacteria. Contributions to this monograph were chosen to highlight this new perspective on antibody responses to infection, as well as to convey its practical implications, such as for contemporary vaccine design.

Table of contents (6 chapters)

Table of contents (6 chapters)
  • Pattern Recognition by B Cells: The Role of Antigen Repetitiveness Versus Toll-Like Receptors

    Hinton, H. J. (et al.)

    Pages 1-15

  • The Multifunctional Role of Antibodies in the Protective Response to Bacterial T Cell-Independent Antigens

    Mond, J. J. (et al.)

    Pages 17-40

  • B Cell Lineage Contributions to Antiviral Host Responses

    Baumgarth, N. (et al.)

    Pages 41-61

  • The Important and Diverse Roles of Antibodies in the Host Response to Borrelia Infections

    LaRocca, T. J. (et al.)

    Pages 63-103

  • A Distinct Role for B1b Lymphocytes in T Cell-Independent Immunity

    Alugupalli, K. R.

    Pages 105-130

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-540-73900-5
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-3-540-73899-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
price for USA in USD
  • ISBN 978-3-642-09313-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Specialization and Complementation of Humoral Immune Responses to Infection
Editors
  • Tim Manser
Series Title
Current Topics in Microbiology and Immunology
Series Volume
319
Copyright
2008
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-73900-5
DOI
10.1007/978-3-540-73900-5
Hardcover ISBN
978-3-540-73899-2
Softcover ISBN
978-3-642-09313-5
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XII, 162
Topics