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Advances in Anatomy, Embryology and Cell Biology

Neuroendocrine Cells and Peptidergic Innervation in Human and Rat Prostrate

Authors: Santamaria, L., Ingelmo, I., Alonso, L., Pozuelo, J.M., Rodríguez, R.

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  • The prostate hosts important neuroendocrine cells whose origin and functional roles must be better understood
  • This study examines the neuroendocrine cell population from the transition zone of the human prostate
  • Includes the observation that the neuroendocrine cells and the peptidergic innervation of rat prostate might be influenced by aging and androgenic status
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About this book

1 Introduction The prostate causes a signi?cant number of medical problems in the adult male, and the lower urinary tract symptoms are accepted as an unavoidable consequence of male aging. Most of these symptoms are mainly due to clinical benign prostatic hyperplasia (BPH), which is the most frequent benign tumor in the male, in- pendent of race or culture. On the other hand, cancer of the prostate shows an increasing incidence, being the second leading cause of death in men, after lung cancer. It has an etiology related to multiple factors: age, race, androgen dep- dence, chemical agents, diet, etc. Both pathologies are very costly in terms of medical resources, and they s- ni?cantly diminish quality of life. More than 400,000 prostate resections per year are done in the US, and these result in an approximate cost of 5 billion dollars per year. Because of all these circumstances, a better knowledge of the mechanisms regulating normal, hyperplastic, and neoplastic prostate growth is important for treatment and prevention of BPH and prostate cancer. Since the last review about prostate neuroendocrine cells published in 1998 there have been new and exciting developments relating to these cells in both normal and pathologic prostate. The cross talk of signals between epithelial and neuroendocrine cells seems relevant to the development and physiopathology of the prostate; thus the relationship between these cell populations should be more deeply studied.

Table of contents (7 chapters)

Table of contents (7 chapters)
  • Introduction

    Pages 1-2

  • The Human Prostate

    Pages 2-11

    Santamaría, L. (et al.)

  • The Neuroendocrine System and the Human Prostate

    Pages 12-29

    Santamaría, L. (et al.)

  • Innervation and Neuroendocrine Cells in Both Normal and Hyperplastic Prostate

    Pages 29-38

    Santamaría, L. (et al.)

  • The Prostate of the Rat

    Pages 38-42

    Ingelmo, I. (et al.)

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-540-69816-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $169.99
price for USA in USD
  • ISBN 978-3-540-69815-9
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Neuroendocrine Cells and Peptidergic Innervation in Human and Rat Prostrate
Authors
Series Title
Advances in Anatomy, Embryology and Cell Biology
Series Volume
194
Copyright
2007
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-69816-6
DOI
10.1007/978-3-540-69816-6
Softcover ISBN
978-3-540-69815-9
Series ISSN
0301-5556
Edition Number
1
Number of Pages
XI, 80
Topics

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