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Handbook of Experimental Pharmacology

Antisense Research and Application

Editors: Crooke, Stanley T. (Ed.)

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eBook $429.00
price for USA in USD (gross)
  • ISBN 978-3-642-58785-6
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Hardcover $549.99
price for USA in USD
  • ISBN 978-3-540-63833-9
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Softcover $549.99
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  • ISBN 978-3-642-63730-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Antisense technology may result in dramatic changes in the therapy of many diseases and may provide tools to dissect pharmacological processes and to confirm the roles of various genes. In this volume, progress in the understanding of antisense technology and its use in creating new drugs is discussed. Potential caveats, pitfalls and limitations of the technology are also presented. In the next few years the pace at which new molecular targets will be identified will increase exponentially as the sequencing of the human genome and of other genomes proceeds.

Table of contents (21 chapters)

  • Basic Principles of Antisense Therapeutics

    Crooke, S. T.

    Pages 1-50

  • Antisense Medicinal Chemistry

    Cook, P. D.

    Pages 51-101

  • In Vitro Cellular Uptake, Distribution, and Metabolism of Oligonucleotides

    Crooke, R. M.

    Pages 103-140

  • Pharmacokinetic Properties of Phosphorothioates in Animals — Absorption, Distribution, Metabolism and Elimination

    Nicklin, P. L. (et al.)

    Pages 141-168

  • Toxicity of Oligodeoxynucleotide Therapeutic Agents

    Levin, A. A. (et al.)

    Pages 169-215

Buy this book

eBook $429.00
price for USA in USD (gross)
  • ISBN 978-3-642-58785-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $549.99
price for USA in USD
  • ISBN 978-3-540-63833-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $549.99
price for USA in USD
  • ISBN 978-3-642-63730-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Antisense Research and Application
Editors
  • Stanley T. Crooke
Series Title
Handbook of Experimental Pharmacology
Series Volume
131
Copyright
1998
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-58785-6
DOI
10.1007/978-3-642-58785-6
Hardcover ISBN
978-3-540-63833-9
Softcover ISBN
978-3-642-63730-8
Series ISSN
0171-2004
Edition Number
1
Number of Pages
XXVI, 630
Number of Illustrations
112 b/w illustrations, 6 illustrations in colour
Topics