Current Topics in Microbiology and Immunology

Dendritic Cells and Virus Infection

Editors: Steinkasserer, Alexander (Ed.)

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About this book

Dendritic cells (DC) are vital to induce potent anti-viral immune responses. However, viruses have developed a large number of different escape mechanisms in order to overcome the host immune system. A prime target in this respect are DC, since they are the only antigen presenting cell able to induce also naive T cells. In the present CTMI-volume the interaction between several viruses, including HIV-1, SIV, EBV, measles virus, LCMV and HSV-1, with DC will be described and discussed. It will become clear to the reader that DC often play a dual role during viral infections. On the one hand they are able to mount potent antiviral immune responses, and the other hand several viruses, including HIV-1, use DC as a vector to be transferred from the periphery to the lymph nodes were they infect their prime target cells. In the second part of this volume several DC specific immune intervention strategies will be presented. This includes topics such as DC vaccination strategies in immunotherapy, viral vectors for the genetic modification of DC and cross presentation of virus infected cells by DC.

Table of contents (13 chapters)

Table of contents (13 chapters)
  • The Interaction of Immunodeficiency Viruses with Dendritic Cells

    Steinman, R. M. (et al.)

    Pages 1-30

  • DC-SIGN: A Novel HIV Receptor on DCs That Mediates HIV-1 Transmission

    Geijtenbeek, T. B. H. (et al.)

    Pages 31-54

  • Contrasting Roles of Dendritic Cells and B Cells in the Immune Control of Epstein-Barr Virus

    Bickham, K. (et al.)

    Pages 55-76

  • Dendritic Cells and Measles Virus Infection

    Schneider-Schaulies, S. (et al.)

    Pages 77-101

  • Measles Virus and Dendritic Cell Functions: How Specific Response Cohabits with Immunosuppression

    Servet-Delprat, C. (et al.)

    Pages 103-123

Buy this book

eBook $179.00
price for USA in USD (gross)
  • ISBN 978-3-662-06508-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-3-540-44290-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.99
price for USA in USD
  • ISBN 978-3-642-07926-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Dendritic Cells and Virus Infection
Editors
  • Alexander Steinkasserer
Series Title
Current Topics in Microbiology and Immunology
Series Volume
276
Copyright
2003
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-662-06508-2
DOI
10.1007/978-3-662-06508-2
Hardcover ISBN
978-3-540-44290-5
Softcover ISBN
978-3-642-07926-9
Series ISSN
0070-217X
Edition Number
1
Number of Pages
X, 298
Topics