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- About this book
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In 1972, a very powerful catalytic cycle for carbon-carbon bond formation was 2 first discovered by the coupling reaction of Grignard reagents at the sp -carbon. Over the past 30 years, the protocol has been substantially improved and expanded to other coupling reactions of Li,B,N,O,Al,Si,P,S,Cu,Mn,Zn,In,Sn, and Hg compounds. These reactions provided an indispensable and simple methodology for preparative organic chemists. Due to the simplicity and rel- bility in the carbon-carbon, carbon-heteroatom, and carbon-metalloid bo- formations,as well as high efficiency of the catalytic process,the reactions have been widely employed by organic chemists in various fields. Application of the protocol ranges from various syntheses of complex natural products to the preparation of biologically relevant molecules including drugs, and of sup- molecules, and to functional materials. The reactions on solid surfaces allow robot synthesis and combinatorial synthesis. Now, many organic chemists do not hesitate to use transition metal complexes for the transformation of org- ic molecules. Indeed, innumerable organic syntheses have been realized by the catalyzed reactions of transition metal complexes that are not achievable by t- ditional synthetic methods. Among these, the metal-catalyzed cross-coupling reactions have undoubtedly contributed greatly to the development of such a new area of “metal-catalyzed organic syntheses”. An excellent monograph for the cross-coupling reactions and other met- catalyzed C-C bond-forming reactions recently appeared in Metal-catalyzed Cross-coupling Reactions (Wiley-VCH,1998).
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It is also suitable for teaching advanced courses in organic and organometallic chemistry. Clearly, it is one of the best books in this important field of synthetic organic chemistry.
- Table of contents (6 chapters)
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Introduction to Cross-Coupling Reactions
Pages 1-9
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Organoboron Compounds
Pages 11-59
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Organosilicon Compounds
Pages 61-85
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Organotin Compounds
Pages 87-130
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Practical Palladium Catalysts for C-N and C-O Bond Formation
Pages 131-209
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Table of contents (6 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Cross-Coupling Reactions
- Book Subtitle
- A Practical Guide
- Editors
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- Norio Miyaura
- Series Title
- Topics in Current Chemistry
- Series Volume
- 219
- Copyright
- 2002
- Publisher
- Springer-Verlag Berlin Heidelberg
- Copyright Holder
- Springer-Verlag Berlin Heidelberg
- eBook ISBN
- 978-3-540-45313-0
- DOI
- 10.1007/3-540-45313-X
- Hardcover ISBN
- 978-3-540-42175-7
- Softcover ISBN
- 978-3-642-07576-6
- Series ISSN
- 0340-1022
- Edition Number
- 1
- Number of Pages
- X, 248
- Topics
