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Cooperation of Liver Cells in Health and Disease

  • Book
  • © 2001

Overview

Authors:
  1. Zbigniew Kmieć

    1. Department of Histology and Immunology, Medical University of Gdansk, Gdansk, Poland

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Part of the book series: Advances in Anatomy, Embryology and Cell Biology (ADVSANAT, volume 161)

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Table of contents (16 chapters)

  1. Front Matter

    Pages N2-XII
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  2. Introduction — Morphology of the Liver Lobule

    1. Introduction — Morphology of the Liver Lobule

      • Zbigniew Kmieć
      Pages 1-6

  3. Cells of the Liver Lobule

    1. Front Matter

      Pages 7-7
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    2. Hepatocytes

      • Zbigniew Kmieć
      Pages 9-12

    3. Sinusoidal Endothelial Cells

      • Zbigniew Kmieć
      Pages 13-19

    4. Kupffer Cells

      • Zbigniew Kmieć
      Pages 21-28

    5. Hepatic Stellate Cells

      • Zbigniew Kmieć
      Pages 29-39

    6. Pit Cells and Other Intrahepatic Lymphocytes

      • Zbigniew Kmieć
      Pages 41-46

  4. Cross-Talk of Liver Cells in Physiology and Pathology

    1. Front Matter

      Pages 47-50
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    2. Cooperation of Liver Cells in the Synthesis and Degradation of Eicosanoids

      • Zbigniew Kmieć
      Pages 51-59

    3. Nitric Oxide as a Mediator of Intercellular Communication in the Liver

      • Zbigniew Kmieć
      Pages 61-64

    4. Cooperation of Hepatocytes and Stellate Cells in the Metabolism and Storage of Retinoids

      • Zbigniew Kmieć
      Pages 65-67

    5. Cooperation of Liver Cells in the Regulation of Glucose Metabolism

      • Zbigniew Kmieć
      Pages 69-72

    6. Cooperation of Liver Cells in the Synthesis of Growth Factors and Respective Binding Proteins

      • Zbigniew Kmieć
      Pages 73-78

    7. Cooperation of Liver Cells in the Regulation of Sinusoidal Contractility

      • Zbigniew Kmieć
      Pages 79-82

    8. Cross-Talk of Liver Cells in Response to Endotoxin

      • Zbigniew Kmieć
      Pages 83-96

    9. Cooperation of Liver Cells in the Process of Liver Fibrosis

      • Zbigniew Kmieć
      Pages 97-105

    10. Perspectives

      • Zbigniew Kmieć
      Pages 107-108

    11. Summary

      • Zbigniew Kmieć
      Pages 109-113

  5. Back Matter

    Pages 115-151
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Keywords

About this book

It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.

Authors and Affiliations

  • Department of Histology and Immunology, Medical University of Gdansk, Gdansk, Poland

    Zbigniew Kmieć

Bibliographic Information

  • Book Title: Cooperation of Liver Cells in Health and Disease

  • Authors: Zbigniew Kmieć

  • Series Title: Advances in Anatomy, Embryology and Cell Biology

  • DOI: https://doi.org/10.1007/978-3-642-56553-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2001

  • Softcover ISBN: 978-3-540-41887-0Published: 28 August 2001

  • eBook ISBN: 978-3-642-56553-3Published: 29 June 2013

  • Series ISSN: 0301-5556

  • Series E-ISSN: 2192-7065

  • Edition Number: 1

  • Number of Pages: XIII, 151

  • Number of Illustrations: 18 b/w illustrations

  • Topics: Life Sciences, general, Human Physiology, Cell Biology, Hepatology

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