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Alzheimer: 100 Years and Beyond

  • Book
  • © 2006

Overview

Editors:
  1. Mathias Jucker

    1. Department of Cellular Neurology Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany

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  2. Konrad Beyreuther

    1. Centre for Molecular Biology, The University of Heidelberg, Heidelberg, Germany

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  3. Christian Haass

    1. Adolf-Butenandt-Institute Department of Biochemistry Laboratory for Alzheimer’s and Parkinson’s Disease Research, Ludwig-Maximilians-University, Munich, Germany

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  4. Roger M. Nitsch

    1. Division of Psychiatry Research, University of Zurich, Zurich, Switzerland

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  5. Yves Christen

    1. Pour la Recherche Thérapeutique, Foundation IPSEN, Paris Cedex 16, France

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Part of the book series: Research and Perspectives in Alzheimer's Disease (ALZHEIMER)

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Table of contents (59 chapters)

  1. Front Matter

    Pages I-XXXIII
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  3. The beginning of modern research

    1. Front Matter

      Pages 57-57
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    2. Alzheimer’s Disease at mid-Century (1927–1977) and a little more

      • Robert D. Terry
      Pages 59-61

    3. A chapter in the development on Alzheimer’s disease research

      • Zaven S. Khachaturian
      Pages 63-86

  4. Anatomy & Neuropsychology

    1. Front Matter

      Pages 87-87
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    2. Anatomical changes underlying dementia in Alzheimer’s disease

      • Bradley T. Hyman
      Pages 89-94

    3. Staging of cortical neurofibrillary inclusions of the Alzheimer’s type

      • Heiko Braak, Kelly Del Tredici
      Pages 97-106

    4. Of stains and brains: a brief account of how microscopic and clinical observations contributed to the understanding of Alzheimer’s disease

      • Charles Duyckaerts, Jean-Jacques Hauw
      Pages 109-113

    5. Presenile forms of Alzheimer’s disease in 2006

      • Michel Poncet, Olivier Felician, Jean-François Pellissier
      Pages 115-119

  5. Cholinergic Deficit

    1. Front Matter

      Pages 121-121
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    2. The cholinergic deficit in Alzheimer’s disease

      • Peter Davies
      Pages 123-125

    3. Acetylcholine in AD: Expectations meet reality

      • John H. Growdon
      Pages 127-132

  6. Amyloid and Genetics

    1. Front Matter

      Pages 133-133
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    2. The Discovery of β Amyloid

      • Cai’ne W. Wong
      Pages 135-140

    3. Pathways to the discovery of the neuronal origin and proteolytic biogenesis of Aβ amyloid of Alzheimer’s disease

      • Colin L Masters, Konrad Beyreuther
      Pages 143-149
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Keywords

About this book

Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4, 1906 in Tübingen.

The celebratory event, "Alzheimer 100 Years and Beyond" organized on the initiation of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, was the highlight of the Year of Alzheimer. However, beyond these few months of tributes, the centennial offers a unique opportunity to assess both the progress achieved and the uncertainties remaining. This volume, a collection comprised mainly of articles by the invited speakers and also of a few other prominent researchers, is meant to be a record of those events.

Editors and Affiliations

  • Department of Cellular Neurology Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany

    Mathias Jucker

  • Centre for Molecular Biology, The University of Heidelberg, Heidelberg, Germany

    Konrad Beyreuther

  • Adolf-Butenandt-Institute Department of Biochemistry Laboratory for Alzheimer’s and Parkinson’s Disease Research, Ludwig-Maximilians-University, Munich, Germany

    Christian Haass

  • Division of Psychiatry Research, University of Zurich, Zurich, Switzerland

    Roger M. Nitsch

  • Pour la Recherche Thérapeutique, Foundation IPSEN, Paris Cedex 16, France

    Yves Christen

Bibliographic Information

  • Book Title: Alzheimer: 100 Years and Beyond

  • Editors: Mathias Jucker, Konrad Beyreuther, Christian Haass, Roger M. Nitsch, Yves Christen

  • Series Title: Research and Perspectives in Alzheimer's Disease

  • DOI: https://doi.org/10.1007/978-3-540-37652-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2006

  • Hardcover ISBN: 978-3-540-37651-4Published: 25 October 2006

  • Softcover ISBN: 978-3-642-07232-1Published: 23 November 2010

  • eBook ISBN: 978-3-540-37652-1Published: 22 November 2006

  • Series ISSN: 0945-6066

  • Series E-ISSN: 2196-310X

  • Edition Number: 1

  • Number of Pages: XXXIV, 544

  • Number of Illustrations: 52 b/w illustrations, 143 illustrations in colour

  • Topics: Neurosciences

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