Current Topics in Microbiology and Immunology

Chemokines and Viral Infection

Editors: Lane, Thomas E. (Ed.)

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About this book

This edition of Current Topics in Microbiology and Immunology examines the role of chemokines and chemokine receptors in host defense and disease development following viral infection. Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory diseases and it was recognized that expression may be integral in leukocyte recruitment to inflamed tissue. There are now four sub-families of chemokines identified based on defined structural criteria relating to the positional location of conserved cysteine residues within the amino-terminus of the protein. Chemokines are now recognized as important in numerous biological processes ranging from maintaining the organizational integrity of secondary lymphoid tissue to participating in various aspects of both innate and adaptive immune responses following microbial infection. With this in mind, this book highlights the functional roles of chemokines and their receptors in participating in various aspects of the immune response against well-known viral pathogens.

Table of contents (6 chapters)

Table of contents (6 chapters)
  • Functional Diversity of Chemokines and Chemokine Receptors in Response to Viral Infection of the Central Nervous System

    Pages 1-27

    Lane, T. E. (et al.)

  • Cytokine and Chemokine Networks: Pathways to Antiviral Defense

    Pages 29-46

    Salazar-Mather, T. P. (et al.)

  • Herpes Simplex Virus and the Chemokines That Mediate the Inflammation

    Pages 47-65

    Carr, D. J. J. (et al.)

  • Influence of Proinflammatory Cytokines and Chemokines on the Neuropathogenesis of Oncornavirus and Immunosuppressive Lentivirus Infections

    Pages 67-95

    Peterson, K. E. (et al.)

  • HIV-1 Coreceptors and Their Inhibitors

    Pages 97-120

    Ray, N. (et al.)

Buy this book

eBook $169.00
price for USA in USD
  • ISBN 978-3-540-33397-5
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-3-540-29207-4
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $219.99
price for USA in USD
  • ISBN 978-3-642-06717-4
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Chemokines and Viral Infection
Editors
  • Thomas E. Lane
Series Title
Current Topics in Microbiology and Immunology
Series Volume
303
Copyright
2006
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-33397-5
DOI
10.1007/978-3-540-33397-5
Hardcover ISBN
978-3-540-29207-4
Softcover ISBN
978-3-642-06717-4
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XI, 160
Topics