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Research and Perspectives in Endocrine Interactions

Hormones and the Brain

Editors: Kordon, Claude, Gaillard, Rolf-Christian (Eds.)

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About this book

Peripheral hormones have a major impact on the brain: they are able to interfere with its development, to affect release of neurotransmitters and concentrations of receptors, to trigger growth factors involved in lesion repair. These multiple actions account for their capacity to modulate a number of physiological parameters, from reproductive functions to memory, behaviour and aging. Depending upon intensity and duration of exposure, they can be either neuroprotective or neurotoxic, for instance by affecting production of free radicals. This book, based on contributions of pioneer investigators in the field, outlines the ambiguous actions of gonadal steroids (estradiol, progesterone, testosterone, inhibin and activin) and of neurosteroids, related moieties produced in the brain itself. After summarizing their multiple mechanisms of action, which involve both direct effects on neuronal membranes and activation of genes coding for specific proteins in neurons or glial cells, the book outlines the role of hormones in pathogenic processes such as mental disturbances or neurodegenerative diseases.

Table of contents (13 chapters)

Table of contents (13 chapters)
  • Activins and inhibins: Physiological roles, signaling mechanisms and regulation

    Pages 1-28

    Gray, Peter C. (et al.)

  • Twins and the fetal origins hypothesis: An application to growth data

    Pages 29-46

    Boomsma, Dorret (et al.)

  • Towards Understanding the Neurobiology of Mammalian Puberty: Genetic, Genomic and Proteomic Approaches

    Pages 47-60

    Ojeda, Sergio R. (et al.)

  • The non-genomic Action of Sex Steroids

    Pages 61-72

    Joe, I (et al.)

  • Mechanisms of Steroid Hormone Actions on Hypothalamic Nerve Cells: Molecular and Biophysical Studies relevant for Hormone-dependent Behaviors

    Pages 73-77

    Kow, Lee-Ming (et al.)

Buy this book

eBook $109.00
price for USA in USD
  • ISBN 978-3-540-26940-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
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Bibliographic Information

Bibliographic Information
Book Title
Hormones and the Brain
Editors
  • Claude Kordon
  • Rolf-Christian Gaillard
Series Title
Research and Perspectives in Endocrine Interactions
Copyright
2005
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-26940-3
DOI
10.1007/b138340
Series ISSN
1861-2253
Edition Number
1
Number of Pages
XVII, 238
Number of Illustrations
53 b/w illustrations, 16 illustrations in colour
Topics

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