Current Topics in Microbiology and Immunology

Immunology and Immunopathogenesis of Malaria

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About this book

Malaria is still a major global health problem, killing more than 1 million people every year. Almost all of these deaths are caused by Plasmodium falciparum, one of the four species of malaria parasites infecting humans. This high burden of mortality falls heavily on Sub-Saharan Africa, where over 90% of these deaths are thought to occur, and 5% of children die before the age of 5 years. The death toll from malaria is still growing, with malaria-specific mortality in young African children estimated to have doubled during the last twenty years. This increase has been associated with drug resistance of the parasite, spread of insecticide resistant mosquitoes, poverty, social and political upheaval, and lack of effective vaccines.

This collection of reviews addresses many of these important issues of malarial immunity and immunopathology. They are of interest not only to malariologists, but hopefully also to the broader immunological community. Strong interactions with, and feedback from immunologists working in other infectious diseases and in basic immunology will help us to move the field of malaria immunology and therapeutic intervention forward more quickly.

Table of contents (6 chapters)

Table of contents (6 chapters)
  • The Dissection of CD8 T Cells During Liver-Stage Infection

    Krzych, U. (et al.)

    Pages 1-24

  • Early Interactions Between Blood-Stage Plasmodium Parasites and the Immune System

    Urban, B. C. (et al.)

    Pages 25-70

  • Longevity of the Immune Response and Memory to Blood-Stage Malaria Infection

    Achtman, A. H. (et al.)

    Pages 71-102

  • ExperimentalModels of Cerebral Malaria

    Engwerda, C. (et al.)

    Pages 103-143

  • Glycosylphosphatidylinositols in Malaria Pathogenesis and Immunity: Potential for Therapeutic Inhibition and Vaccination

    Boutlis, C. S. (et al.)

    Pages 145-185

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-3-540-29967-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-3-540-25718-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-3-642-42184-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Immunology and Immunopathogenesis of Malaria
Series Title
Current Topics in Microbiology and Immunology
Series Volume
297
Copyright
2005
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-29967-7
DOI
10.1007/3-540-29967-X
Hardcover ISBN
978-3-540-25718-9
Softcover ISBN
978-3-642-42184-6
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XI, 234
Topics