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Advances in Anatomy, Embryology and Cell Biology
cover

Molecular Parameters Indicating Adaptation to Mechanical Stress in Fibrous Connective Tissue

Authors: Milz, Stefan, Benjamin, Michael, Putz, Reinhard

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About this book

The present study pursues the hypothesis that local compressive force and the occurrence of cartilage-specific transformation processes within tendons and ligaments are directly correlated.

In selected anatomical samples of human origin the distribution pattern of certain components of the extracellular matrix is assessed. Investigations are carried out at the extensor tendons of toes and fingers, at the transverse ligament of the atlas, at the transverse ligament of the acetabulum, and at the tendon of the superior oblique muscle and its trochlea. The molecular components of the extracellular matrix are detected with standardized immunohistochemical methods.

The results show that certain molecules only occur due to compressive stress, others due to tensile stress. The molecular spectrum of the extracellular matrix allows qualifying conclusions to the mechanical situation of a given part of the tissue.

The spatial expansion of the fibrocartilaginous adaptation zones in tendons and ligaments roughly corresponds with the zones subjected to compressive force; tensile stress alone does not result in a production of fibrocartilage.

Table of contents (7 chapters)

Table of contents (7 chapters)
  • Introduction

    Pages 1-4

  • Aim of the Study

    Pages 5-7

  • Anatomical Structures Investigated

    Pages 9-16

  • Materials and Methods

    Pages 17-22

  • Results

    Pages 23-41

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-540-27832-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $169.99
price for USA in USD
  • ISBN 978-3-540-24474-5
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Molecular Parameters Indicating Adaptation to Mechanical Stress in Fibrous Connective Tissue
Authors
Series Title
Advances in Anatomy, Embryology and Cell Biology
Series Volume
178
Copyright
2005
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-27832-0
DOI
10.1007/3-540-27832-X
Softcover ISBN
978-3-540-24474-5
Series ISSN
0301-5556
Edition Number
1
Number of Pages
VI, 74
Topics

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