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Advances in Anatomy, Embryology and Cell Biology

Proliferation of Different Cell Types in the Brain

Authors: Korr, Hubert

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About this book

Studies on cell kinetics in untreated animals have for the most part been done on or­ gans in which many proliferating cells can be found. In general the proliferating cells have been identified either in histologic sections as mitoses or by autoradiography as labeled interphase cells following the injection of a labeled precursor of DNA, such as 3H_ or 14C-thymidine (TdR). A great many proliferating cells can be observed in the rat and mouse brain during the embryonic period and for a short time after birth, and many studies on cell kinetics have been performed for this phase of life. By contrast, very few proliferating cells are found in the brain of adult rodents (except for the subependymallayer, see below). As a result, only isolated studies have been done on cell kinetics during this period. Al­ though there is an increase in proliferating cells in adult animals which had been pre­ treated (e g. , by wounding, X-irradiation, viral infection, withdrawal of water), this proliferation too has not been investigated in detail. A number of studies have been done since 1959 on the proliferation of cells in the sub­ ependymal layer of the lateral ventricles of the forebrain. This cell type is well suited for such investigations because mitoses can be found there even in animals which are quite old. Since the studies ofLe blond and co-workers (Walker and Leblond 1958 ;Messier et al.

Table of contents (6 chapters)

Table of contents (6 chapters)
  • Introduction

    Pages 1-3

    Korr, Dr. rer. nat. Dr. med. habil. Hubert

  • Thymidine Labeling as an Indication of Cell Proliferation

    Pages 3-5

    Korr, Dr. rer. nat. Dr. med. habil. Hubert

  • Period of Proliferation of Different Cell Types in the Rat and Mouse Brain

    Pages 5-16

    Korr, Dr. rer. nat. Dr. med. habil. Hubert

  • Cell Cycle Parameters of the Different Cell Types in the Rodent Brain During Pre- and Postnatal Ontogeny

    Pages 17-35

    Korr, Dr. rer. nat. Dr. med. habil. Hubert

  • Mode of Proliferation

    Pages 35-56

    Korr, Dr. rer. nat. Dr. med. habil. Hubert

Buy this book

eBook $99.00
price for USA in USD (gross)
  • ISBN 978-3-642-67577-5
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA in USD
  • ISBN 978-3-540-09899-7
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Proliferation of Different Cell Types in the Brain
Authors
Series Title
Advances in Anatomy, Embryology and Cell Biology
Series Volume
61
Copyright
1980
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer Verlag Berlin Heidelberg
eBook ISBN
978-3-642-67577-5
DOI
10.1007/978-3-642-67577-5
Softcover ISBN
978-3-540-09899-7
Series ISSN
0301-5556
Edition Number
1
Number of Pages
VIII, 74
Number of Illustrations
2 b/w illustrations
Topics

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