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Advances in Anatomy, Embryology and Cell Biology

Nuclear Volume and Cellular Metabolism

Authors: Hildebrand, Reinhard

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About this book

The application of morphometric techniques in biology and the development ofbioche­ mical methods for cytological-histological research have deepened substantially our knowledge and understanding of the structure, dynamics, and function of morphologi­ cal structures, thereby improving upon a purely descriptive presentation. Thus the limits between the individual disciplines in basic research have become blurred. With the development of suitable methods of measuring the size of nuclear volu­ mes, it has become possible to obtain data regarding the variable state and nucleo­ kinetic processes in the "genetic center of control" of the cell (Siebert 1967), and to evaluate these data statistically so as to make them verifiable. With the formulation of the "basic law of karyometry" by Palkovits and Fischer (1968), in a dynamic approach to "genetic" and "functional trends" in karyometry, i. e. , an attempt to relate nuclear volume changes exclusively to the size and number of chromosomes, and, on the other hand, to comprehend these changes as an expression of functional changes, successfully connected with one another and interpreted bio­ logically. The early function-oriented observation that a swelling of the nuclear volume is an expression of an increase in cellular function, while a decrease in the volume is an indication of a lowering of activity, provided a preliminary basis for estimating nu­ clear size as a statement about the functional state of a tissue or organ.

Table of contents (6 chapters)

Table of contents (6 chapters)

Buy this book

eBook $99.00
price for USA in USD
  • ISBN 978-3-642-67503-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA in USD
  • ISBN 978-3-540-09796-9
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Nuclear Volume and Cellular Metabolism
Authors
Series Title
Advances in Anatomy, Embryology and Cell Biology
Series Volume
60
Copyright
1980
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-67503-4
DOI
10.1007/978-3-642-67503-4
Softcover ISBN
978-3-540-09796-9
Series ISSN
0301-5556
Edition Number
1
Number of Pages
VIII, 56
Number of Illustrations
1 b/w illustrations
Topics