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  • Book
  • Open Access
  • © 2019

Fundamentals of Clinical Data Science

  • Provides a resource for healthcare professionals on smart algorithms

  • Integrates the data, modelling, clinical application levels of clinical data science

  • Focuses on relevant non math and code aspects for physicians

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-viii
  2. Data Collection

    1. Front Matter

      Pages 1-1
    2. Data Sources

      • Pieter Kubben
      Pages 3-9Open Access
    3. Data at Scale

      • Alberto Traverso, Frank J. W. M. Dankers, Leonard Wee, Sander M. J. van Kuijk
      Pages 11-17Open Access
    4. Standards in Healthcare Data

      • Stefan Schulz, Robert Stegwee, Catherine Chronaki
      Pages 19-36Open Access
    5. Research Data Stewardship for Healthcare Professionals

      • Paula Jansen, Linda van den Berg, Petra van Overveld, Jan-Willem Boiten
      Pages 37-53Open Access
    6. The EU’s General Data Protection Regulation (GDPR) in a Research Context

      • Christopher F. Mondschein, Cosimo Monda
      Pages 55-71Open Access
  3. From Data to Model

    1. Front Matter

      Pages 73-73
    2. Preparing Data for Predictive Modelling

      • Sander M. J. van Kuijk, Frank J. W. M. Dankers, Alberto Traverso, Leonard Wee
      Pages 75-84Open Access
    3. Extracting Features from Time Series

      • Christian Herff, Dean J. Krusienski
      Pages 85-100Open Access
    4. Prediction Modeling Methodology

      • Frank J. W. M. Dankers, Alberto Traverso, Leonard Wee, Sander M. J. van Kuijk
      Pages 101-120Open Access
    5. Diving Deeper into Models

      • Alberto Traverso, Frank J. W. M. Dankers, Biche Osong, Leonard Wee, Sander M. J. van Kuijk
      Pages 121-133Open Access
    6. Reporting Standards and Critical Appraisal of Prediction Models

      • Leonard Wee, Sander M. J. van Kuijk, Frank J. W. M. Dankers, Alberto Traverso, Mattea Welch, Andre Dekker
      Pages 135-150Open Access
  4. From Model to Application

    1. Front Matter

      Pages 151-151
    2. Clinical Decision Support Systems

      • A. T. M. Wasylewicz, A. M. J. W. Scheepers-Hoeks
      Pages 153-169Open Access
    3. Mobile Apps

      • Pieter Kubben
      Pages 171-179Open Access
    4. Optimizing Care Processes with Operational Excellence & Process Mining

      • Henri J. Boersma, Tiffany I. Leung, Rob Vanwersch, Elske Heeren, G. G. van Merode
      Pages 181-192Open Access
    5. Value-Based Health Care Supported by Data Science

      • Tiffany I. Leung, G. G. van Merode
      Pages 193-212Open Access
  5. Correction to: Prediction Modeling Methodology

    • Frank J. W. M. Dankers, Alberto Traverso, Leonard Wee, Sander M. J. van Kuijk
    Pages C1-C1Open Access
  6. Back Matter

    Pages 213-219

About this book

This open access book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications.  Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and  related privacy concerns. Aspects of  predictive modelling  using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare.

Fundamentals of Clinical Data Science is an essential resource for healthcare professionals and IT consultants intending to develop and refine their skills in personalized medicine, using solutions based on large datasets from electronic health records or telemonitoring programmes. The book’s promise is “no math, no code”and will explain the topics in a style that is optimized for a healthcare audience.


Editors and Affiliations

  • Department of Neurosurgery, Maastricht University, Maastricht, Limburg, The Netherlands

    Pieter Kubben

  • Institute of Data Science, Maastricht University, Maastricht, Limburg, The Netherlands

    Michel Dumontier

  • Maastro Clinic, Maastricht, Limburg, The Netherlands

    Andre Dekker

About the editors

Pieter Kubben is a neurosurgeon, mobile app developer and programme manager for eHealth and mHealth for the Maastricht University Medical Center. Telemonitoring and corresponding algorithm development is a particular focus area Dr Kubben is involved in, as well as interactive clinical decision support systems.

Michel Dumontier is a distuinguished professor of data science at Maastricht University and head of the Institute for Data Science – connecting data science initiatives and projects from all faculties. He is also deeply involved in the FAIR data approach (Findable, Accessible, Interoperable, Reproducible).

André Dekker is a professor of clinical data science at Maastricht University and has been leading the development of prediction models in radiation therapy for many years. He is also coordinator of the Personal Health Train project, aiming to facilitate “citizen science”.



Bibliographic Information

  • Book Title: Fundamentals of Clinical Data Science

  • Editors: Pieter Kubben, Michel Dumontier, Andre Dekker

  • DOI: https://doi.org/10.1007/978-3-319-99713-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s) 2019

  • License: CC BY

  • Hardcover ISBN: 978-3-319-99712-4Published: 07 January 2019

  • eBook ISBN: 978-3-319-99713-1Published: 21 December 2018

  • Edition Number: 1

  • Number of Pages: VIII, 219

  • Number of Illustrations: 10 b/w illustrations, 35 illustrations in colour

  • Topics: Health Informatics, Computational Biology/Bioinformatics

Buy it now

Buying options

Hardcover Book USD 59.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access