Current Topics in Microbiology and Immunology

Escherichia coli, a Versatile Pathogen

Editors: Frankel, Gad, Ron, Eliora Z (Eds.)

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  • Provides new insights into the genetics, physiology and pathogenesis of E. coli
  • Broadens readers’ understanding of the various types of E. coli infections
  • Offers an overview of E. coli as part of the microbial intestinal biofilms, the microbiome and its evolution
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eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-319-99664-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-319-99663-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Escherichia coli is a facultative anaerobic Gamma-proteobacterium, which belongs to the family Enterobacteriaceae. While being an important constituent of the normal gut microbiota, specialized E. coli clones have acquired genetic elements that allow them to compete with the endogenous commensals, colonise normally sterile niches and cause disease. E. coli pathotypes can cause intestinal and extra intestinal infections (e.g. UTI, sepsis) and associate with mammalian cells while being extra- or intra-cellular. In recent years, E. coli infections have become a serious clinical problem, due to the rapid spread of antibiotic resistance. Thus, infections with intestinal E. coli (e.g. E. coli O104) or extraintestinal pathogenic strains (e.g. E. coli ST131) are becoming difficult to treat and are often lethal. Consequently, there is a pressing need to develop alternative control measures, including the identification of new drug targets and development of vaccines that offer lasting protection.

This volume focuses on several types of E. coli infections (intestinal and extraintestinal), virulence factors, and E. coli pandemics. It addresses the problem of antibiotic resistance, and a dedicated chapter discusses the need to develop alternative control measures. Given its depth and breadth of coverage, the book will benefit all those interested in the biology, genetics, physiology and pathogenesis of E. coli, and in related vaccine development.


About the authors

Prof. Dr. Gad FrankelDepartment of Life Sciences, Faculty of Natural Sciences, Imperial College London, London, United Kingdom, g.frankel@imperial.ac.uk 

Prof. Dr. Eliora Z. RonDepartment of Molecular Microbiology and Biotechnology, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel, eliora@post.tau.ac.il

Table of contents (9 chapters)

Table of contents (9 chapters)

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-319-99664-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-319-99663-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Escherichia coli, a Versatile Pathogen
Editors
  • Gad Frankel
  • Eliora Z Ron
Series Title
Current Topics in Microbiology and Immunology
Series Volume
416
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-319-99664-6
DOI
10.1007/978-3-319-99664-6
Hardcover ISBN
978-3-319-99663-9
Series ISSN
0070-217X
Edition Number
1
Number of Pages
VII, 242
Number of Illustrations
20 b/w illustrations, 20 illustrations in colour
Topics